C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin VIIA
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137474 MYO7A 9606 + 11:77128264-77215239 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000409619 MYO7A-009 77128302-77214954 protein_coding
  ENST00000409709 MYO7A-001 77128264-77215238 protein_coding
  ENST00000409893 MYO7A-005 77128270-77184996 protein_coding
  ENST00000458169 MYO7A-010 77179825-77215238 protein_coding
  ENST00000458637 MYO7A-002 77128270-77215238 protein_coding
  ENST00000467137 MYO7A-007 77184686-77191187 retained_intron
  ENST00000481328 MYO7A-003 77179825-77215238 retained_intron
  ENST00000481532 MYO7A-008 77212535-77213918 retained_intron
  ENST00000526863 MYO7A-011 77210887-77212975 processed_transcript
  ENST00000605744 MYO7A-004 77203186-77215239 processed_transcript
  ENST00000620575 MYO7A-201 77128270-77184989 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000409709ENST00000409893ENST00000458169ENST00000458637ENST00000605744ENST00000620575
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000409709 N/A N/A 0.578±0.00 0.233±0.00 0.151±0.00 N/A N/A 0.588±0.00 0.513±0.27 N/A N/A 0.712±0.19 1.338±0.00 N/A
ENST00000409893 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.424±0.00
ENST00000458169 1.540±0.00 5.185±0.00 N/A 0.748±0.50 2.129±0.00 0.409±0.00 1.253±0.00 1.517±0.00 3.178±0.00 0.293±0.17 0.267±0.11 1.674±0.27 14.211±4.03 2.258±0.53
ENST00000458637 N/A N/A N/A N/A N/A N/A N/A 2.190±0.00 N/A 0.059±0.00 0.054±0.00 0.649±0.00 2.981±0.00 0.881±0.43
ENST00000605744 N/A N/A N/A N/A N/A N/A 0.567±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000620575 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.175±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001X7 CIL_0001X7_0002 CGP 11:77102840-77215239
CIL_0001JF CIL_0001JF_0002 CGP 11:77128264-77301687

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000146 IDA microfilament motor activity
GO:0001750 IDA photoreceptor outer segment
GO:0001845 IEA phagolysosome assembly
GO:0001917 IDA photoreceptor inner segment
GO:0003774 IEA motor activity
GO:0003779 IEA actin binding
GO:0005515 IPI:IEA protein binding
GO:0005516 IMP calmodulin binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005765 IDA lysosomal membrane
GO:0005829 IDA cytosol
GO:0005856 IEA cytoskeleton
GO:0005902 IEA microvillus
GO:0006200 IEA ATP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006909 IEA phagocytosis
GO:0007040 IDA lysosome organization
GO:0007600 IEA sensory perception
GO:0007601 IMP visual perception
GO:0007605 IMP sensory perception of sound
GO:0008152 IDA metabolic process
GO:0016324 IEA apical plasma membrane
GO:0016459 IEA myosin complex
GO:0019904 IEA protein domain specific binding
GO:0030030 IEA cell projection organization
GO:0030048 IDA actin filament-based movement
GO:0030507 IDA spectrin binding
GO:0030898 IEA actin-dependent ATPase activity
GO:0031477 IEA myosin VII complex
GO:0032391 IEA photoreceptor connecting cilium
GO:0032403 IEA protein complex binding
GO:0032420 IEA stereocilium
GO:0042462 IC eye photoreceptor cell development
GO:0042470 IEA melanosome
GO:0042472 IEA inner ear morphogenesis
GO:0042490 IEA mechanoreceptor differentiation
GO:0042491 IEA auditory receptor cell differentiation
GO:0042803 IEA protein homodimerization activity
GO:0043531 IEA ADP binding
GO:0045202 IDA synapse
GO:0048563 IEA post-embryonic organ morphogenesis
GO:0048839 IEA inner ear development
GO:0050953 IMP sensory perception of light stimulus
GO:0050957 IMP equilibrioception
GO:0051015 IDA actin filament binding
GO:0051875 IEA pigment granule localization
GO:0051904 IEA pigment granule transport
GO:0060088 IEA auditory receptor cell stereocilium organization
GO:0060113 IEA inner ear receptor cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044632 myo7ab myosin VIIAb protein_coding Danio_rerio
ENSDARG00000061937 myo7aa myosin VIIAa protein_coding Danio_rerio
ENSMUSG00000030761 Myo7a myosin VIIA protein_coding Mus_musculus

Loading