C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin VIIA
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030761 Myo7a 10090 - 7:98051060-98119524 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084979 Myo7a-002 98051327-98109248 protein_coding
  ENSMUST00000107122 Myo7a-003 98051327-98109248 protein_coding
  ENSMUST00000107127 Myo7a-004 98051276-98119503 protein_coding
  ENSMUST00000107128 Myo7a-001 98051060-98119524 protein_coding
  ENSMUST00000124787 Myo7a-012 98062643-98065202 retained_intron
  ENSMUST00000131632 Myo7a-007 98108732-98119492 processed_transcript
  ENSMUST00000138627 Myo7a-006 98098256-98119493 protein_coding
  ENSMUST00000149079 Myo7a-010 98098247-98103357 processed_transcript
  ENSMUST00000152975 Myo7a-011 98081170-98084719 processed_transcript
  ENSMUST00000153657 Myo7a-008 98097613-98112662 protein_coding
  ENSMUST00000155637 Myo7a-009 98098207-98103361 processed_transcript
  ENSMUST00000156992 Myo7a-005 98051063-98069377 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084979ENSMUST00000107122ENSMUST00000107127ENSMUST00000107128ENSMUST00000124787ENSMUST00000156992
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084979 N/A 13.136±1.28 N/A N/A 0.714±0.15 0.396±0.13 N/A N/A 0.504±0.17 0.596±0.00 0.236±0.00 4.041±0.73 N/A N/A
ENSMUST00000107122 N/A N/A 1.019±0.22 N/A N/A 0.619±0.13 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000107127 0.586±0.00 N/A 1.074±0.00 N/A 0.545±0.00 0.484±0.00 0.226±0.07 0.997±0.10 0.429±0.13 N/A 0.227±0.03 3.099±1.50 0.318±0.00 N/A
ENSMUST00000107128 0.775±0.13 13.043±2.35 2.736±0.39 0.869±0.00 N/A 0.286±0.00 0.146±0.00 2.032±0.57 1.288±0.49 2.128±0.11 0.162±0.02 4.768±3.46 2.518±0.81 7.606±2.82
ENSMUST00000124787 N/A 46.868±3.96 N/A N/A N/A 2.202±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000156992 1.924±0.73 N/A 4.455±1.86 3.018±0.58 N/A 0.716±0.00 0.481±0.00 2.549±0.09 2.835±1.27 N/A 0.314±0.00 10.266±4.48 4.262±1.82 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001I4 CIL_0001I4_0002 CGP 7:97919955-98119524

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000146 IEA microfilament motor activity
GO:0001750 ISS photoreceptor outer segment
GO:0001845 IMP phagolysosome assembly
GO:0001917 ISS photoreceptor inner segment
GO:0003774 IEA motor activity
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005516 ISS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005765 ISS lysosomal membrane
GO:0005829 ISS cytosol
GO:0005902 ISA microvillus
GO:0006200 IEA ATP catabolic process
GO:0006886 IMP intracellular protein transport
GO:0006909 IMP phagocytosis
GO:0007040 ISS lysosome organization
GO:0007600 IMP sensory perception
GO:0007601 ISS visual perception
GO:0007605 ISS sensory perception of sound
GO:0008152 IEA metabolic process
GO:0016324 IDA apical plasma membrane
GO:0016459 IEA myosin complex
GO:0019904 IPI protein domain specific binding
GO:0030030 IMP cell projection organization
GO:0030048 IEA actin filament-based movement
GO:0030507 ISO spectrin binding
GO:0030898 IEA actin-dependent ATPase activity
GO:0031477 IEA myosin VII complex
GO:0032391 IDA photoreceptor connecting cilium
GO:0032403 IEA protein complex binding
GO:0032420 IDA stereocilium
GO:0042470 IDA melanosome
GO:0042472 IMP inner ear morphogenesis
GO:0042490 IMP mechanoreceptor differentiation
GO:0042491 IMP auditory receptor cell differentiation
GO:0042803 IEA protein homodimerization activity
GO:0043531 IEA ADP binding
GO:0045202 ISS synapse
GO:0048563 IMP post-embryonic organ morphogenesis
GO:0048839 IMP inner ear development
GO:0050953 IMP sensory perception of light stimulus
GO:0050957 IEA equilibrioception
GO:0051015 IEA actin filament binding
GO:0051875 IMP pigment granule localization
GO:0051904 IMP pigment granule transport
GO:0060088 IMP auditory receptor cell stereocilium organization
GO:0060113 IMP inner ear receptor cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044632 myo7ab myosin VIIAb protein_coding Danio_rerio
ENSDARG00000061937 myo7aa myosin VIIAa protein_coding Danio_rerio
ENSG00000137474 MYO7A myosin VIIA protein_coding Homo_sapiens

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