C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: arrestin, beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137486 ARRB1 9606 - 11:75264182-75351705 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360025 ARRB1-002 75265599-75351705 protein_coding
  ENST00000420843 ARRB1-001 75264182-75351705 protein_coding
  ENST00000524400 ARRB1-004 75278677-75312155 nonsense_mediated_decay
  ENST00000527385 ARRB1-007 75278716-75303670 nonsense_mediated_decay
  ENST00000529280 ARRB1-009 75281614-75284313 retained_intron
  ENST00000529741 ARRB1-011 75272786-75276911 retained_intron
  ENST00000530086 ARRB1-010 75281006-75282132 retained_intron
  ENST00000531012 ARRB1-003 75270930-75274938 retained_intron
  ENST00000532447 ARRB1-012 75266116-75278699 protein_coding
  ENST00000532525 ARRB1-006 75274200-75306709 protein_coding
  ENST00000533255 ARRB1-008 75281878-75351660 retained_intron
  ENST00000533609 ARRB1-005 75278711-75312124 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360025ENST00000420843ENST00000524400ENST00000527385ENST00000531012ENST00000532447ENST00000533255
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360025 10.372±0.00 15.878±0.00 1.417±0.00 9.500±6.68 8.114±5.68 2.817±1.99 5.016±2.91 2.164±0.11 12.858±3.44 1.099±0.33 7.821±3.64 28.371±7.71 2.651±0.85
ENST00000420843 4.328±0.00 8.993±0.00 N/A N/A 2.097±0.00 N/A 1.133±0.79 1.296±0.00 3.120±0.00 0.084±0.00 4.181±1.36 8.877±2.01 N/A
ENST00000524400 N/A N/A N/A N/A 2.868±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000527385 N/A N/A N/A N/A N/A N/A 6.015±0.00 N/A N/A N/A N/A N/A N/A
ENST00000531012 N/A N/A N/A N/A N/A N/A 0.655±0.00 N/A N/A N/A N/A N/A N/A
ENST00000532447 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.343±0.00
ENST00000533255 N/A N/A 4.571±0.00 N/A 7.306±0.00 N/A N/A 10.077±0.00 21.818±0.00 N/A 2.278±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I3 CIL_0008I3_0001 VISTA 11:74770295-75374240
CIL_0008NG CIL_0008NG_0001 VISTA 11:75253021-75855707

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0000785 IDA chromatin
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002031 IMP G-protein coupled receptor internalization
GO:0002092 IMP positive regulation of receptor internalization
GO:0004857 TAS enzyme inhibitor activity
GO:0005096 IMP GTPase activator activity
GO:0005159 IPI insulin-like growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005765 TAS lysosomal membrane
GO:0005829 TAS cytosol
GO:0005834 TAS heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006892 TAS post-Golgi vesicle-mediated transport
GO:0007165 IEA signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0007596 TAS blood coagulation
GO:0007602 IEA phototransduction
GO:0008134 IPI transcription factor binding
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0015031 IEA protein transport
GO:0016567 IMP protein ubiquitination
GO:0030168 TAS platelet activation
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031143 IEA pseudopodium
GO:0031397 IDA negative regulation of protein ubiquitination
GO:0031410 IDA cytoplasmic vesicle
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031701 IPI angiotensin receptor binding
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032092 IEA positive regulation of protein binding
GO:0032715 IDA negative regulation of interleukin-6 production
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0035025 IMP positive regulation of Rho protein signal transduction
GO:0035066 IMP positive regulation of histone acetylation
GO:0035774 IEA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0043027 IEA cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043149 IMP stress fiber assembly
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IMP positive regulation of GTPase activity
GO:0044212 IMP transcription regulatory region DNA binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0061024 TAS membrane organization
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090240 IMP positive regulation of histone H4 acetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043241 arrb1 arrestin, beta 1 protein_coding Danio_rerio
ENSMUSG00000018909 Arrb1 arrestin, beta 1 protein_coding Mus_musculus

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