C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: arrestin, beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018909 Arrb1 10090 + 7:99535466-99606771 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032995 Arrb1-002 99535662-99603574 protein_coding
  ENSMUST00000098266 Arrb1-001 99535466-99606771 protein_coding
  ENSMUST00000159642 Arrb1-008 99594614-99601155 retained_intron
  ENSMUST00000161268 Arrb1-005 99573064-99588128 processed_transcript
  ENSMUST00000161525 Arrb1-004 99539669-99588136 protein_coding
  ENSMUST00000162043 Arrb1-007 99594593-99601141 retained_intron
  ENSMUST00000162290 Arrb1-009 99594623-99600081 protein_coding
  ENSMUST00000162404 Arrb1-006 99535704-99588941 protein_coding
  ENSMUST00000162933 Arrb1-003 99594621-99599801 retained_intron
  ENSMUST00000179755 Arrb1-201 99535466-99606771 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032995ENSMUST00000098266ENSMUST00000179755
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032995 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.072±1.32 3.342±0.44 2.911±1.36
ENSMUST00000098266 17.975±1.00 5.476±2.07 15.223±0.82 14.854±7.11 14.480±3.46 14.370±4.04 3.428±0.59 11.562±3.75 25.483±26.80 52.324±0.65 2.280±0.70 6.652±3.29 9.930±5.95 2.473±0.00
ENSMUST00000179755 N/A N/A N/A N/A N/A N/A 1.267±0.00 1.504±0.00 N/A N/A N/A N/A 0.644±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NG CIL_0008NG_0002 VISTA 7:99059661-99661402
CIL_0008I3 CIL_0008I3_0002 VISTA 7:99464975-100069320

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000785 IEA chromatin
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0002031 IEA G-protein coupled receptor internalization
GO:0002092 ISS positive regulation of receptor internalization
GO:0005096 IEA GTPase activator activity
GO:0005159 IEA insulin-like growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0005905 IEA coated pit
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007602 IMP phototransduction
GO:0008134 IEA transcription factor binding
GO:0008277 IMP regulation of G-protein coupled receptor protein signaling pathway
GO:0015031 IEA protein transport
GO:0016567 IEA protein ubiquitination
GO:0031143 IDA pseudopodium
GO:0031397 IEA negative regulation of protein ubiquitination
GO:0031410 IEA cytoplasmic vesicle
GO:0031434 IDA mitogen-activated protein kinase kinase binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0031701 IEA angiotensin receptor binding
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032092 IMP positive regulation of protein binding
GO:0032715 IEA negative regulation of interleukin-6 production
GO:0032717 IEA negative regulation of interleukin-8 production
GO:0033138 IMP positive regulation of peptidyl-serine phosphorylation
GO:0035025 IEA positive regulation of Rho protein signal transduction
GO:0035066 IEA positive regulation of histone acetylation
GO:0035774 IMP positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0043027 IMP cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043149 IEA stress fiber assembly
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0090240 IEA positive regulation of histone H4 acetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043241 arrb1 arrestin, beta 1 protein_coding Danio_rerio
ENSG00000137486 ARRB1 arrestin, beta 1 protein_coding Homo_sapiens

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