C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: arrestin, beta 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000360025 ARRB1-002 ENSG00000137486 9606 - 11:75265599-75351705 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360025
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360025 10.372±0.00 15.878±0.00 1.417±0.00 9.500±6.68 8.114±5.68 2.817±1.99 5.016±2.91 2.164±0.11 12.858±3.44 1.099±0.33 7.821±3.64 28.371±7.71 2.651±0.85

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008I3 CIL_0008I3_0001 VISTA 11:74770295-75374240
CIL_0008NG CIL_0008NG_0001 VISTA 11:75253021-75855707

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0000785 IDA chromatin
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0002031 IMP G-protein coupled receptor internalization
GO:0002092 IMP positive regulation of receptor internalization
GO:0004857 TAS enzyme inhibitor activity
GO:0005096 IMP GTPase activator activity
GO:0005159 IPI insulin-like growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005765 TAS lysosomal membrane
GO:0005829 TAS cytosol
GO:0005834 TAS heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006892 TAS post-Golgi vesicle-mediated transport
GO:0007219 TAS Notch signaling pathway
GO:0007596 TAS blood coagulation
GO:0008134 IPI transcription factor binding
GO:0015031 IEA protein transport
GO:0016567 IMP protein ubiquitination
GO:0030168 TAS platelet activation
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031397 IDA negative regulation of protein ubiquitination
GO:0031410 IDA cytoplasmic vesicle
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031701 IPI angiotensin receptor binding
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032715 IDA negative regulation of interleukin-6 production
GO:0032717 IDA negative regulation of interleukin-8 production
GO:0035025 IMP positive regulation of Rho protein signal transduction
GO:0035066 IMP positive regulation of histone acetylation
GO:0043149 IMP stress fiber assembly
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IMP positive regulation of GTPase activity
GO:0044212 IMP transcription regulatory region DNA binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0061024 TAS membrane organization
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090240 IMP positive regulation of histone H4 acetylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000032995 Arrb1-002 protein_coding Mus_musculus 0 1858
ENSMUST00000098266 Arrb1-001 protein_coding Mus_musculus 0 1759
ENSMUST00000179755 Arrb1-201 protein_coding Mus_musculus 0 1735
ENSMUST00000162043 Arrb1-007 retained_intron Mus_musculus 0 486
ENSMUST00000159642 Arrb1-008 retained_intron Mus_musculus 0 412
ENSMUST00000161525 Arrb1-004 protein_coding Mus_musculus 0 385
ENSMUST00000161268 Arrb1-005 processed_transcript Mus_musculus 0 379
ENSMUST00000162404 Arrb1-006 protein_coding Mus_musculus 0 298

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