C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sulfatase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137573 SULF1 9606 + 8:69466624-69660915 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260128 SULF1-201 69466624-69660912 protein_coding
  ENST00000402687 SULF1-004 69492761-69660055 protein_coding
  ENST00000419716 SULF1-003 69492793-69660055 protein_coding
  ENST00000458141 SULF1-001 69466624-69660915 protein_coding
  ENST00000521946 SULF1-005 69592910-69659408 processed_transcript
  ENST00000524731 SULF1-020 69625954-69629571 processed_transcript
  ENST00000525061 SULF1-008 69466624-69564064 protein_coding
  ENST00000525112 SULF1-013 69562813-69563877 retained_intron
  ENST00000525999 SULF1-015 69563862-69586460 protein_coding
  ENST00000526654 SULF1-022 69638811-69641147 retained_intron
  ENST00000526808 SULF1-017 69564096-69586508 processed_transcript
  ENST00000528146 SULF1-019 69592939-69597547 processed_transcript
  ENST00000528286 SULF1-009 69466817-69495850 processed_transcript
  ENST00000528783 SULF1-014 69563442-69576027 protein_coding
  ENST00000529041 SULF1-011 69492832-69563697 retained_intron
  ENST00000529134 SULF1-010 69466987-69576051 protein_coding
  ENST00000530674 SULF1-007 69637604-69659407 retained_intron
  ENST00000531064 SULF1-016 69564048-69589120 processed_transcript
  ENST00000531512 SULF1-006 69627804-69660051 nonsense_mediated_decay
  ENST00000532015 SULF1-021 69638691-69658892 retained_intron
  ENST00000534088 SULF1-018 69592884-69597592 processed_transcript
  ENST00000534179 SULF1-012 69562808-69564144 protein_coding
  ENST00000616868 SULF1-202 69492793-69642296 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260128ENST00000402687ENST00000419716ENST00000458141ENST00000521946ENST00000524731ENST00000531064ENST00000531512ENST00000616868
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260128 N/A N/A N/A N/A N/A N/A 0.359±0.09 N/A N/A N/A N/A 1.264±0.00 0.996±0.16 N/A
ENST00000402687 N/A 2.342±0.00 N/A 0.677±0.00 3.565±2.72 1.017±0.00 N/A N/A N/A 1.397±0.61 N/A 1.955±0.47 1.400±0.00 N/A
ENST00000419716 2.267±0.00 3.774±0.00 1.698±0.00 0.873±0.00 7.374±6.17 5.180±2.35 1.413±0.42 3.181±0.00 3.101±0.00 1.152±0.76 0.344±0.05 4.727±1.96 2.391±1.16 3.375±2.21
ENST00000458141 0.359±0.00 N/A 0.323±0.00 0.437±0.10 3.483±0.00 0.749±0.00 0.532±0.00 N/A 2.148±0.00 0.621±0.00 N/A 2.451±0.22 0.622±0.09 N/A
ENST00000521946 N/A N/A N/A N/A N/A N/A N/A 0.262±0.00 N/A N/A 0.420±0.00 6.981±0.00 N/A 6.072±0.00
ENST00000524731 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.116±0.00 8.997±0.00
ENST00000531064 N/A N/A N/A N/A N/A N/A N/A 1.077±0.00 N/A N/A N/A N/A N/A N/A
ENST00000531512 1.002±0.00 6.634±0.00 N/A 1.205±0.00 2.622±0.00 12.973±0.00 N/A 2.923±0.00 0.224±0.00 N/A 0.458±0.00 8.096±1.29 1.042±0.00 6.899±0.00
ENST00000616868 0.793±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SG CIL_0001SG_0002 CGP 8:68330722-69660915
CIL_00087Y CIL_00087Y_0001 VISTA 8:69097307-69699884
CIL_0001S3 CIL_0001S3_0002 CGP 8:69466624-69835064

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 ISS kidney development
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0002063 ISS chondrocyte development
GO:0003094 ISS glomerular filtration
GO:0003824 IEA catalytic activity
GO:0004065 IDA arylsulfatase activity
GO:0005509 IEA calcium ion binding
GO:0005615 NAS extracellular space
GO:0005783 IDA:IEA endoplasmic reticulum
GO:0005794 ISS:IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0006915 IEA apoptotic process
GO:0008152 IEA metabolic process
GO:0008449 IDA N-acetylglucosamine-6-sulfatase activity
GO:0008484 IEA sulfuric ester hydrolase activity
GO:0009986 IDA:IEA cell surface
GO:0010575 ISS positive regulation vascular endothelial growth factor production
GO:0014846 ISS esophagus smooth muscle contraction
GO:0016525 IDA negative regulation of angiogenesis
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030201 NAS heparan sulfate proteoglycan metabolic process
GO:0030336 IMP negative regulation of cell migration
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0032836 ISS glomerular basement membrane development
GO:0035860 ISS glial cell-derived neurotrophic factor receptor signaling pathway
GO:0040036 IMP regulation of fibroblast growth factor receptor signaling pathway
GO:0040037 ISS negative regulation of fibroblast growth factor receptor signaling pathway
GO:0045121 IDA membrane raft
GO:0048010 IDA vascular endothelial growth factor receptor signaling pathway
GO:0048706 ISS embryonic skeletal system development
GO:0051216 ISS cartilage development
GO:0060348 ISS bone development
GO:0060384 ISS innervation
GO:0060686 ISS negative regulation of prostatic bud formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038428 sulf1 sulfatase 1 protein_coding Danio_rerio
ENSMUSG00000016918 Sulf1 sulfatase 1 protein_coding Mus_musculus

Loading