C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sulfatase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000016918 Sulf1 10090 + 1:12692277-12861192 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000088585 Sulf1-004 12718529-12860377 protein_coding
  ENSMUST00000177608 Sulf1-001 12692277-12861192 protein_coding
  ENSMUST00000180062 Sulf1-002 12692323-12860371 protein_coding
  ENSMUST00000185780 Sulf1-009 12842791-12861192 protein_coding
  ENSMUST00000186051 Sulf1-008 12692532-12852489 protein_coding
  ENSMUST00000186405 Sulf1-006 12728119-12786639 protein_coding
  ENSMUST00000186674 Sulf1-007 12785443-12788818 retained_intron
  ENSMUST00000187376 Sulf1-003 12718459-12822916 retained_intron
  ENSMUST00000189447 Sulf1-010 12836028-12840497 retained_intron
  ENSMUST00000189541 Sulf1-005 12719464-12786549 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000088585ENSMUST00000177608ENSMUST00000180062ENSMUST00000185780ENSMUST00000186051ENSMUST00000187376
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000088585 7.122±2.84 0.603±0.22 6.887±0.61 1.821±0.26 3.720±0.85 0.725±0.31 1.476±0.74 0.879±0.18 0.071±0.02 3.539±0.91 0.646±0.33 2.503±1.22 0.419±0.20 0.711±0.15
ENSMUST00000177608 2.853±1.89 0.383±0.00 2.543±0.13 3.617±1.92 N/A N/A 1.048±0.08 0.266±0.07 0.286±0.13 1.934±0.21 0.469±0.10 2.613±0.27 0.425±0.47 N/A
ENSMUST00000180062 2.099±1.47 1.476±0.46 N/A 4.924±3.40 1.082±0.11 1.391±0.73 1.721±0.56 0.285±0.06 0.237±0.19 3.276±1.01 0.481±0.06 3.239±1.17 0.356±0.23 0.739±0.20
ENSMUST00000185780 N/A N/A 5.592±0.47 2.496±0.88 1.755±0.00 0.838±0.00 N/A N/A 0.167±0.05 N/A 0.653±0.24 1.391±0.00 0.262±0.09 0.743±0.17
ENSMUST00000186051 N/A N/A N/A N/A N/A 0.262±0.00 N/A N/A 0.033±0.00 N/A N/A N/A N/A 0.673±0.05
ENSMUST00000187376 N/A N/A N/A N/A N/A 0.738±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SG CIL_0001SG_0003 CGP 1:11414105-12861192
CIL_00087Y CIL_00087Y_0002 VISTA 1:12314812-12917322
CIL_0001S3 CIL_0001S3_0003 CGP 1:12692277-12992650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001502 ISS cartilage condensation
GO:0001822 IGI kidney development
GO:0001937 ISS negative regulation of endothelial cell proliferation
GO:0002063 IMP chondrocyte development
GO:0003094 IGI glomerular filtration
GO:0004065 ISS arylsulfatase activity
GO:0005509 IEA calcium ion binding
GO:0005615 ISS extracellular space
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0006790 ISO sulfur compound metabolic process
GO:0006915 IEA apoptotic process
GO:0007155 ISS cell adhesion
GO:0008449 ISO N-acetylglucosamine-6-sulfatase activity
GO:0009986 ISS cell surface
GO:0010575 IGI positive regulation vascular endothelial growth factor production
GO:0014846 IGI esophagus smooth muscle contraction
GO:0016525 ISS negative regulation of angiogenesis
GO:0030177 ISS positive regulation of Wnt signaling pathway
GO:0030201 IMP heparan sulfate proteoglycan metabolic process
GO:0030336 ISS negative regulation of cell migration
GO:0030513 ISS positive regulation of BMP signaling pathway
GO:0032836 IGI glomerular basement membrane development
GO:0035860 IDA glial cell-derived neurotrophic factor receptor signaling pathway
GO:0036022 ISS limb joint morphogenesis
GO:0040036 IEA regulation of fibroblast growth factor receptor signaling pathway
GO:0040037 IGI negative regulation of fibroblast growth factor receptor signaling pathway
GO:0045121 ISS membrane raft
GO:0048010 ISS vascular endothelial growth factor receptor signaling pathway
GO:0048661 ISS positive regulation of smooth muscle cell proliferation
GO:0048706 IGI embryonic skeletal system development
GO:0051216 IMP cartilage development
GO:0060348 IGI bone development
GO:0060384 IGI innervation
GO:0060686 IDA negative regulation of prostatic bud formation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038428 sulf1 sulfatase 1 protein_coding Danio_rerio
ENSG00000137573 SULF1 sulfatase 1 protein_coding Homo_sapiens

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