C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sulfatase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000458141 SULF1-001 ENSG00000137573 9606 + 8:69466624-69660915 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartLiverLungOvaryPlacentaENST00000458141
Transcript ID Adipose Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta
ENST00000458141 0.359±0.00 0.323±0.00 0.437±0.10 3.483±0.00 0.749±0.00 0.532±0.00 2.148±0.00 0.621±0.00 2.451±0.22 0.622±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001SG CIL_0001SG_0002 CGP 8:68330722-69660915
CIL_00087Y CIL_00087Y_0001 VISTA 8:69097307-69699884
CIL_0001S3 CIL_0001S3_0002 CGP 8:69466624-69835064

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 ISS kidney development
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0002063 ISS chondrocyte development
GO:0003094 ISS glomerular filtration
GO:0003824 IEA catalytic activity
GO:0004065 IDA arylsulfatase activity
GO:0005509 IEA calcium ion binding
GO:0005615 NAS extracellular space
GO:0005783 IDA:IEA endoplasmic reticulum
GO:0005794 ISS:IEA Golgi apparatus
GO:0005886 ISS plasma membrane
GO:0006915 IEA apoptotic process
GO:0008152 IEA metabolic process
GO:0008449 IDA N-acetylglucosamine-6-sulfatase activity
GO:0008484 IEA sulfuric ester hydrolase activity
GO:0009986 IDA:IEA cell surface
GO:0010575 ISS positive regulation vascular endothelial growth factor production
GO:0014846 ISS esophagus smooth muscle contraction
GO:0016525 IDA negative regulation of angiogenesis
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030201 NAS heparan sulfate proteoglycan metabolic process
GO:0030336 IMP negative regulation of cell migration
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0032836 ISS glomerular basement membrane development
GO:0035860 ISS glial cell-derived neurotrophic factor receptor signaling pathway
GO:0040036 IMP regulation of fibroblast growth factor receptor signaling pathway
GO:0040037 ISS negative regulation of fibroblast growth factor receptor signaling pathway
GO:0045121 IDA membrane raft
GO:0048010 IDA vascular endothelial growth factor receptor signaling pathway
GO:0048706 ISS embryonic skeletal system development
GO:0051216 ISS cartilage development
GO:0060348 ISS bone development
GO:0060384 ISS innervation
GO:0060686 ISS negative regulation of prostatic bud formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000177608 Sulf1-001 protein_coding Mus_musculus 0 3779
ENSMUST00000088585 Sulf1-004 protein_coding Mus_musculus 0 3356
ENSMUST00000180062 Sulf1-002 protein_coding Mus_musculus 0 3273
ENSMUST00000186051 Sulf1-008 protein_coding Mus_musculus 0 3173
ENSMUST00000187376 Sulf1-003 retained_intron Mus_musculus 0 1827
ENSMUST00000185780 Sulf1-009 protein_coding Mus_musculus 0 366
ENSDART00000056080 sulf1-202 protein_coding Danio_rerio 7e-36 158
ENSDART00000027022 sulf1-201 protein_coding Danio_rerio 7e-36 158
ENSDART00000056081 sulf1-001 protein_coding Danio_rerio 7e-36 158

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