C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, alpha 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137809 ITGA11 9606 - 15:68296533-68432162 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315757 ITGA11-201 68301712-68432153 protein_coding
  ENST00000423218 ITGA11-001 68296533-68432162 protein_coding
  ENST00000562826 ITGA11-009 68351256-68365522 processed_transcript
  ENST00000565868 ITGA11-008 68357079-68361641 retained_intron
  ENST00000566429 ITGA11-006 68331951-68340843 processed_transcript
  ENST00000568677 ITGA11-007 68357145-68361957 retained_intron
  ENST00000569346 ITGA11-005 68331078-68336100 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000315757ENST00000423218ENST00000562826ENST00000565868ENST00000569346
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000315757 1.871±0.00 2.116±0.00 0.232±0.00 0.294±0.23 3.363±1.48 1.168±0.31 2.198±2.08 3.965±0.00 1.455±1.30 0.594±0.30 0.500±0.03 8.163±5.11 2.136±0.34 2.716±2.10
ENST00000423218 N/A N/A N/A 0.029±0.00 0.318±0.00 N/A N/A N/A N/A 0.024±0.00 0.020±0.00 0.739±0.52 0.097±0.00 N/A
ENST00000562826 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.688±0.00 N/A N/A N/A N/A
ENST00000565868 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.738±0.00 N/A N/A N/A
ENST00000569346 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.688±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00046P CIL_00046P_0002 CGP 15:68296533-68727806

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IDA osteoblast differentiation
GO:0005518 IMP collagen binding
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006929 IMP substrate-dependent cell migration
GO:0007155 TAS cell adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007229 IMP integrin-mediated signaling pathway
GO:0007517 TAS muscle organ development
GO:0008305 TAS integrin complex
GO:0016020 IDA membrane
GO:0030198 TAS extracellular matrix organization
GO:0033627 IMP cell adhesion mediated by integrin
GO:0034681 IDA integrin alpha11-beta1 complex
GO:0038064 IMP collagen receptor activity
GO:0038065 IMP collagen-activated signaling pathway
GO:0046872 IEA metal ion binding
GO:0098639 IMP collagen binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007950 itga11b integrin, alpha 11b protein_coding Danio_rerio
ENSDARG00000036086 itga11a integrin, alpha 11a protein_coding Danio_rerio
ENSMUSG00000032243 Itga11 integrin alpha 11 protein_coding Mus_musculus

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