C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032243 Itga11 10090 + 9:62677826-62783982 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034774 Itga11-001 62677826-62783982 protein_coding
  ENSMUST00000159012 Itga11-002 62677860-62777111 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034774ENSMUST00000159012
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034774 3.238±0.14 0.731±0.12 7.065±0.21 0.886±0.63 3.459±1.06 2.234±0.39 0.836±0.23 0.149±0.03 0.051±0.03 0.073±0.00 0.592±0.07 1.981±0.91 0.303±0.22 0.702±0.25
ENSMUST00000159012 N/A 0.175±0.00 N/A N/A N/A 0.569±0.00 0.192±0.07 0.114±0.00 0.024±0.01 0.210±0.10 N/A 0.773±0.00 0.048±0.01 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008FN CIL_0008FN_0002 VISTA 9:62114649-62715677
CIL_00080E CIL_00080E_0002 VISTA 9:62138578-62752434
CIL_0004FA CIL_0004FA_0002 CGP 9:62677826-62811648

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0005518 IEA collagen binding
GO:0005925 IEA focal adhesion
GO:0006929 IEA substrate-dependent cell migration
GO:0007160 IEA cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0016020 IEA membrane
GO:0033627 IEA cell adhesion mediated by integrin
GO:0034681 IEA integrin alpha11-beta1 complex
GO:0038064 IEA collagen receptor activity
GO:0038065 IEA collagen-activated signaling pathway
GO:0098639 IEA collagen binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007950 itga11b integrin, alpha 11b protein_coding Danio_rerio
ENSDARG00000036086 itga11a integrin, alpha 11a protein_coding Danio_rerio
ENSG00000137809 ITGA11 integrin, alpha 11 protein_coding Homo_sapiens

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