C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol-trisphosphate 3-kinase A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137825 ITPKA 9606 + 15:41493393-41503551 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260386 ITPKA-001 41493875-41503551 protein_coding
  ENST00000425927 ITPKA-002 41493393-41502488 protein_coding
  ENST00000462816 ITPKA-003 41501439-41503099 retained_intron
  ENST00000491007 ITPKA-004 41501794-41502645 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000260386ENST00000425927ENST00000462816
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000260386 0.066±0.00 N/A 6.467±5.04 0.113±0.04 1.550±0.47 0.369±0.00 0.089±0.04 0.133±0.00 0.797±0.00 2.563±1.01 0.552±0.26 4.641±2.11
ENST00000425927 N/A 0.438±0.00 N/A N/A N/A 0.440±0.00 N/A N/A N/A N/A N/A 3.566±0.00
ENST00000462816 N/A N/A 8.639±0.00 N/A N/A 0.853±0.00 N/A N/A 0.313±0.00 0.905±0.00 0.130±0.00 2.335±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005FC CIL_0005FC_0001 CGP 15:41408408-41503551
CIL_0002WJ CIL_0002WJ_0002 CGP 15:41493393-41513887

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004683 IEA calmodulin-dependent protein kinase activity
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006020 IEA inositol metabolic process
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0008440 IEA inositol-1,4,5-trisphosphate 3-kinase activity
GO:0016310 IEA phosphorylation
GO:0030036 IEA actin cytoskeleton organization
GO:0043197 IEA dendritic spine
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0048167 IEA regulation of synaptic plasticity
GO:0048365 IEA Rac GTPase binding
GO:0061003 IEA positive regulation of dendritic spine morphogenesis
GO:0097062 IEA dendritic spine maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042856 itpka inositol 1,4,5-trisphosphate 3-kinase A protein_coding Danio_rerio
ENSMUSG00000027296 Itpka inositol 1,4,5-trisphosphate 3-kinase A protein_coding Mus_musculus

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