C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inositol 1,4,5-trisphosphate 3-kinase A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027296 Itpka 10090 + 2:119742337-119751263 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028758 Itpka-001 119742337-119751263 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028758
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028758 1.181±0.48 2.202±1.10 0.327±0.04 34.084±47.92 1.752±0.59 6.880±0.85 0.361±0.23 1.011±0.15 1.828±1.00 4.116±0.26 0.044±0.00 1.887±0.66 9.398±9.46 2.994±0.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005FC CIL_0005FC_0002 CGP 2:119675068-119751263
CIL_0002WJ CIL_0002WJ_0003 CGP 2:119742337-119760431

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004683 IEA calmodulin-dependent protein kinase activity
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0006020 IMP inositol metabolic process
GO:0006468 IEA protein phosphorylation
GO:0008440 IEA inositol-1,4,5-trisphosphate 3-kinase activity
GO:0030036 IEA actin cytoskeleton organization
GO:0043197 IEA dendritic spine
GO:0048167 IMP regulation of synaptic plasticity
GO:0048365 IEA Rac GTPase binding
GO:0061003 IEA positive regulation of dendritic spine morphogenesis
GO:0097062 IEA dendritic spine maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042856 itpka inositol 1,4,5-trisphosphate 3-kinase A protein_coding Danio_rerio
ENSG00000137825 ITPKA inositol-trisphosphate 3-kinase A protein_coding Homo_sapiens

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