C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 1, subfamily B, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138061 CYP1B1 9606 - 2:38066973-38109902 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000490576 CYP1B1-005 38074959-38076154 protein_coding
  ENST00000491456 CYP1B1-007 38066973-38070697 processed_transcript
  ENST00000492443 CYP1B1-006 38070987-38073936 processed_transcript
  ENST00000494864 CYP1B1-009 38070066-38109902 protein_coding
  ENST00000610745 CYP1B1-001 38067507-38076181 protein_coding
  ENST00000613082 CYP1B1-004 38071176-38076154 processed_transcript
  ENST00000614273 CYP1B1-003 38070482-38076076 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000491456ENST00000494864ENST00000610745ENST00000614273
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000491456 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.443±0.00 N/A N/A N/A
ENST00000494864 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.203±0.00 N/A N/A N/A
ENST00000610745 30.913±0.00 15.610±0.00 4.455±0.00 3.090±0.00 2.026±0.87 7.657±0.00 12.535±10.33 1.720±0.22 3.866±1.23 0.339±0.22 3.281±2.42 1.425±0.01 17.577±0.00
ENST00000614273 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.522±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002IP CIL_0002IP_0001 CGP 2:37641882-38067142
CIL_0002IO CIL_0002IO_0001 CGP 2:38066973-38377285

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0002930 ISS trabecular meshwork development
GO:0004497 IDA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005739 ISS mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006725 IEA cellular aromatic compound metabolic process
GO:0006805 IDA xenobiotic metabolic process
GO:0006809 ISS nitric oxide biosynthetic process
GO:0007155 ISS cell adhesion
GO:0007601 TAS visual perception
GO:0008202 IDA steroid metabolic process
GO:0008210 IDA estrogen metabolic process
GO:0008285 ISS negative regulation of cell proliferation
GO:0008631 ISS intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0009404 IEA toxin metabolic process
GO:0009636 IEA response to toxic substance
GO:0010575 ISS positive regulation vascular endothelial growth factor production
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0019369 IDA arachidonic acid metabolic process
GO:0019373 TAS epoxygenase P450 pathway
GO:0019825 TAS oxygen binding
GO:0020037 IEA heme binding
GO:0030199 ISS collagen fibril organization
GO:0030336 ISS negative regulation of cell migration
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0033629 ISS negative regulation of cell adhesion mediated by integrin
GO:0042572 IDA retinol metabolic process
GO:0042574 IDA retinal metabolic process
GO:0043065 ISS positive regulation of apoptotic process
GO:0043542 ISS endothelial cell migration
GO:0044281 TAS small molecule metabolic process
GO:0045766 ISS positive regulation of angiogenesis
GO:0046427 ISS positive regulation of JAK-STAT cascade
GO:0046466 ISS membrane lipid catabolic process
GO:0048514 ISS blood vessel morphogenesis
GO:0055114 IEA oxidation-reduction process
GO:0061298 IEA retina vasculature development in camera-type eye
GO:0061304 ISS retinal blood vessel morphogenesis
GO:0070301 ISS cellular response to hydrogen peroxide
GO:0070330 IEA aromatase activity
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071603 IEA endothelial cell-cell adhesion
GO:0097267 TAS omega-hydroxylase P450 pathway
GO:1901313 ISS positive regulation of gene expression involved in extracellular matrix organization
GO:2000377 ISS regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068934 cyp1b1 cytochrome P450, family 1, subfamily B, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000024087 Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 protein_coding Mus_musculus

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