C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase C, epsilon 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138193 PLCE1 9606 + 10:93993989-94332823 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000260766 PLCE1-201 93993989-94328392 protein_coding
  ENST00000371375 PLCE1-002 94089095-94325609 protein_coding
  ENST00000371380 PLCE1-001 94030812-94332823 protein_coding
  ENST00000371385 PLCE1-202 94089026-94328389 protein_coding
  ENST00000464214 PLCE1-003 94324889-94325656 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000260766ENST00000371380ENST00000371385
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000260766 N/A 1.025±0.00 N/A N/A N/A 0.859±0.44 1.197±0.00 1.048±0.00 2.102±0.00 0.458±0.00 0.143±0.00 0.362±0.00 0.777±0.00
ENST00000371380 0.296±0.00 N/A 0.367±0.03 0.724±0.08 0.761±0.00 0.485±0.10 N/A 0.976±0.00 0.546±0.12 0.326±0.21 1.109±0.62 0.619±0.00 0.559±0.00
ENST00000371385 0.271±0.00 N/A 0.846±0.63 0.678±0.00 2.816±0.00 2.438±0.00 2.350±0.00 N/A 3.091±0.00 0.993±0.00 0.833±0.44 0.940±0.24 0.751±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00067K CIL_00067K_0001 CGP 10:93893973-94332823
CIL_00073K CIL_00073K_0001 CGP 10:93993989-94362959

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0001558 TAS regulation of cell growth
GO:0004435 IDA:IEA phosphatidylinositol phospholipase C activity
GO:0004629 IDA phospholipase C activity
GO:0005057 TAS receptor signaling protein activity
GO:0005085 TAS:IEA guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006644 IC phospholipid metabolic process
GO:0006651 TAS diacylglycerol biosynthetic process
GO:0006940 TAS regulation of smooth muscle contraction
GO:0007010 NAS cytoskeleton organization
GO:0007165 IEA signal transduction
GO:0007173 NAS epidermal growth factor receptor signaling pathway
GO:0007200 IDA phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 TAS positive regulation of cytosolic calcium ion concentration
GO:0007205 NAS protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0007507 TAS heart development
GO:0008081 IEA phosphoric diester hydrolase activity
GO:0008277 IDA regulation of G-protein coupled receptor protein signaling pathway
GO:0008283 NAS cell proliferation
GO:0016042 IEA lipid catabolic process
GO:0017016 TAS Ras GTPase binding
GO:0019722 TAS calcium-mediated signaling
GO:0019899 IPI enzyme binding
GO:0032835 IMP glomerulus development
GO:0035556 IEA intracellular signal transduction
GO:0043547 IEA positive regulation of GTPase activity
GO:0043647 TAS inositol phosphate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045859 IDA regulation of protein kinase activity
GO:0046578 IDA regulation of Ras protein signal transduction
GO:0048016 TAS inositol phosphate-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087921 PLCE1 phospholipase C, epsilon 1 protein_coding Danio_rerio
ENSMUSG00000024998 Plce1 phospholipase C, epsilon 1 protein_coding Mus_musculus

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