C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase C, epsilon 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024998 Plce1 10090 + 19:38481109-38785030 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000169713 Plce1-001 38524197-38785030 protein_coding
  ENSMUST00000181994 Plce1-006 38481109-38524066 processed_transcript
  ENSMUST00000182267 Plce1-003 38524209-38782795 protein_coding
  ENSMUST00000182481 Plce1-002 38481121-38783430 protein_coding
  ENSMUST00000182589 Plce1-004 38722370-38783588 retained_intron
  ENSMUST00000182999 Plce1-007 38583368-38652007 protein_coding
  ENSMUST00000183131 Plce1-005 38734914-38751123 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000169713ENSMUST00000181994ENSMUST00000182267ENSMUST00000182481ENSMUST00000182589
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000169713 0.610±0.00 0.191±0.04 N/A 0.266±0.07 0.285±0.04 1.247±0.31 0.575±0.07 N/A 0.125±0.06 0.596±0.02 0.211±0.05 0.708±0.32 0.053±0.04 0.179±0.00
ENSMUST00000181994 N/A 1.735±0.91 N/A N/A N/A 10.996±0.81 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000182267 0.576±0.22 0.684±0.22 N/A 0.315±0.00 0.901±0.40 2.738±0.12 0.628±0.19 0.489±0.18 0.448±0.17 1.344±0.40 0.311±0.00 1.666±0.79 N/A 0.224±0.01
ENSMUST00000182481 1.346±0.99 0.551±0.31 4.289±0.67 1.105±0.13 0.909±0.30 3.999±1.10 1.819±0.42 0.943±0.19 0.454±0.37 2.602±0.71 0.179±0.06 2.311±0.97 0.211±0.15 0.514±0.15
ENSMUST00000182589 N/A N/A 0.973±0.00 0.305±0.00 0.450±0.00 N/A N/A N/A 0.066±0.02 N/A 0.042±0.00 0.541±0.00 0.092±0.07 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00067K CIL_00067K_0002 CGP 19:38395980-38785030
CIL_00073K CIL_00073K_0002 CGP 19:38481109-38819237

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 ISS activation of MAPK activity
GO:0004435 ISS phosphatidylinositol phospholipase C activity
GO:0004629 ISS phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0007200 ISS phospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008277 ISS regulation of G-protein coupled receptor protein signaling pathway
GO:0016042 IEA lipid catabolic process
GO:0019899 ISS enzyme binding
GO:0032835 IEA glomerulus development
GO:0043547 IEA positive regulation of GTPase activity
GO:0045859 ISS regulation of protein kinase activity
GO:0046578 ISS regulation of Ras protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087921 PLCE1 phospholipase C, epsilon 1 protein_coding Danio_rerio
ENSG00000138193 PLCE1 phospholipase C, epsilon 1 protein_coding Homo_sapiens

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