C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bone morphogenetic protein receptor, type IB
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138696 BMPR1B 9606 + 4:94757968-95158448 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264568 BMPR1B-003 95091491-95154817 protein_coding
  ENST00000394931 BMPR1B-002 95104355-95155016 protein_coding
  ENST00000440890 BMPR1B-201 95051679-95158441 protein_coding
  ENST00000502683 BMPR1B-006 95091434-95115789 protein_coding
  ENST00000506363 BMPR1B-004 94995796-95123835 protein_coding
  ENST00000509540 BMPR1B-007 95051679-95154817 protein_coding
  ENST00000512312 BMPR1B-005 94996232-95154673 protein_coding
  ENST00000515059 BMPR1B-001 94757968-95158448 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394931ENST00000440890ENST00000506363ENST00000509540ENST00000512312ENST00000515059
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394931 0.127±0.00 N/A N/A N/A 0.196±0.00 N/A N/A N/A 0.595±0.00 N/A N/A N/A N/A
ENST00000440890 N/A N/A N/A N/A 0.011±0.00 N/A 0.026±0.00 0.274±0.00 N/A N/A 0.252±0.00 0.047±0.00 N/A
ENST00000506363 N/A N/A N/A N/A N/A 0.552±0.00 N/A N/A 0.772±0.00 N/A N/A N/A N/A
ENST00000509540 N/A 2.686±0.00 3.587±0.00 N/A N/A 0.179±0.00 N/A N/A N/A N/A 1.320±0.00 N/A N/A
ENST00000512312 N/A N/A N/A 1.418±0.00 N/A N/A N/A 0.108±0.00 N/A 0.639±0.00 0.828±0.00 N/A N/A
ENST00000515059 0.162±0.00 N/A 2.545±0.00 N/A 0.170±0.00 0.636±0.00 0.557±0.00 N/A 0.333±0.17 N/A 1.524±1.00 0.112±0.01 2.155±1.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091X CIL_00091X_0001 VISTA 4:94368294-94970308
CIL_0001S9 CIL_0001S9_0002 CGP 4:94451857-95158448
CIL_0005BZ CIL_0005BZ_0002 CGP 4:94757968-95549206

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001502 NAS cartilage condensation
GO:0001550 ISS ovarian cumulus expansion
GO:0001654 ISS eye development
GO:0002062 IEA chondrocyte differentiation
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004675 NAS:IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005025 IEA transforming growth factor beta receptor activity, type I
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0007178 IEA transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0009953 IEA dorsal/ventral pattern formation
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0023014 IEA signal transduction by phosphorylation
GO:0030154 IEA cell differentiation
GO:0030501 IMP positive regulation of bone mineralization
GO:0030509 NAS BMP signaling pathway
GO:0031290 IEA retinal ganglion cell axon guidance
GO:0035108 IMP limb morphogenesis
GO:0042698 ISS ovulation cycle
GO:0043010 IEA camera-type eye development
GO:0043235 TAS receptor complex
GO:0045597 IMP positive regulation of cell differentiation
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0046332 IDA SMAD binding
GO:0046872 IEA metal ion binding
GO:0060041 IEA retina development in camera-type eye
GO:1902043 IEA positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005600 bmpr1ba bone morphogenetic protein receptor, type 1ba protein_coding Danio_rerio
ENSMUSG00000052430 Bmpr1b bone morphogenetic protein receptor, type 1B protein_coding Mus_musculus

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