C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: bone morphogenetic protein receptor, type IB
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000512312 BMPR1B-005 ENSG00000138696 9606 + 4:94996232-95154673 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastLiverMuscleOvaryENST00000512312
Transcript ID Breast Liver Muscle Ovary
ENST00000512312 1.418±0.00 0.108±0.00 0.639±0.00 0.828±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00091X CIL_00091X_0001 VISTA 4:94368294-94970308
CIL_0001S9 CIL_0001S9_0002 CGP 4:94451857-95158448
CIL_0005BZ CIL_0005BZ_0002 CGP 4:94757968-95549206

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001502 NAS cartilage condensation
GO:0001550 ISS ovarian cumulus expansion
GO:0001654 ISS eye development
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004675 NAS:IEA transmembrane receptor protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0023014 IEA signal transduction by phosphorylation
GO:0030501 IMP positive regulation of bone mineralization
GO:0030509 NAS BMP signaling pathway
GO:0035108 IMP limb morphogenesis
GO:0042698 ISS ovulation cycle
GO:0043235 TAS receptor complex
GO:0045597 IMP positive regulation of cell differentiation
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0046332 IDA SMAD binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098568 Bmpr1b-005 protein_coding Mus_musculus 0 1905
ENSMUST00000106230 Bmpr1b-004 protein_coding Mus_musculus 0 1905
ENSMUST00000106232 Bmpr1b-003 protein_coding Mus_musculus 0 1905
ENSMUST00000029948 Bmpr1b-001 protein_coding Mus_musculus 0 1905
ENSMUST00000131273 Bmpr1b-002 nonsense_mediated_decay Mus_musculus 0 1877

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