C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prickle homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139174 PRICKLE1 9606 - 12:42456754-42590355 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345127 PRICKLE1-001 42456754-42589676 protein_coding
  ENST00000445766 PRICKLE1-005 42458355-42590355 protein_coding
  ENST00000455697 PRICKLE1-201 42458338-42483995 protein_coding
  ENST00000547113 PRICKLE1-002 42469505-42589676 protein_coding
  ENST00000548696 PRICKLE1-003 42458951-42483942 protein_coding
  ENST00000551050 PRICKLE1-007 42469477-42483072 protein_coding
  ENST00000552108 PRICKLE1-006 42468736-42484332 protein_coding
  ENST00000552200 PRICKLE1-008 42483813-42589744 processed_transcript
  ENST00000552240 PRICKLE1-004 42459268-42483614 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainHeartLungOvaryENST00000345127ENST00000547113
Transcript ID Adipose Brain Heart Lung Ovary
ENST00000345127 1.218±0.00 2.131±0.15 1.160±0.00 1.400±0.25 2.556±0.86
ENST00000547113 N/A N/A 17.001±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003DG CIL_0003DG_0002 CGP 12:42312078-42590355
CIL_0006R4 CIL_0006R4_0001 CGP 12:42456754-43551921

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006606 IMP protein import into nucleus
GO:0008270 IEA zinc ion binding
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031965 IDA nuclear membrane
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:2000691 IDA negative regulation of cardiac muscle cell myoblast differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040649 prickle1a prickle-like 1 (Drosophila) a protein_coding Danio_rerio
ENSDARG00000045694 prickle1b prickle homolog 1 (Drosophila) b protein_coding Danio_rerio
ENSMUSG00000036158 Prickle1 prickle homolog 1 (Drosophila) protein_coding Mus_musculus

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