C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, beta 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139626 ITGB7 9606 - 12:53191318-53207307 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267082 ITGB7-004 53191318-53207307 protein_coding
  ENST00000422257 ITGB7-005 53191323-53207282 protein_coding
  ENST00000542497 ITGB7-002 53191557-53207281 nonsense_mediated_decay
  ENST00000548269 ITGB7-012 53193677-53194458 retained_intron
  ENST00000548706 ITGB7-009 53192968-53194258 retained_intron
  ENST00000549086 ITGB7-007 53197887-53207254 protein_coding
  ENST00000549196 ITGB7-015 53196101-53197709 retained_intron
  ENST00000549462 ITGB7-001 53196594-53207251 retained_intron
  ENST00000550743 ITGB7-013 53191371-53200443 protein_coding
  ENST00000551319 ITGB7-014 53191323-53192488 protein_coding
  ENST00000551887 ITGB7-008 53195654-53197111 retained_intron
  ENST00000552935 ITGB7-006 53197872-53201300 protein_coding
  ENST00000552972 ITGB7-011 53197591-53207281 protein_coding
  ENST00000589179 ITGB7-016 53196332-53207251 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonLungPlacentaENST00000267082ENST00000422257
Transcript ID Adrenal Colon Lung Placenta
ENST00000267082 N/A 2.226±0.00 3.346±1.85 N/A
ENST00000422257 10.133±0.00 N/A N/A 2.032±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006T6 CIL_0006T6_0001 CGP 12:53157663-53195141
CIL_0006T5 CIL_0006T5_0001 CGP 12:53180700-53207307
CIL_00060L CIL_00060L_0001 CGP 12:53191318-53232980

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001618 IEA virus receptor activity
GO:0003366 IMP cell-matrix adhesion involved in ameboidal cell migration
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0007155 TAS cell adhesion
GO:0007160 IEA:IMP cell-matrix adhesion
GO:0007229 IEA:IMP integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 IEA:TAS integrin complex
GO:0009615 IEA response to virus
GO:0009986 IDA cell surface
GO:0016020 IDA:IEA membrane
GO:0030198 TAS extracellular matrix organization
GO:0034113 IMP heterotypic cell-cell adhesion
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0034669 IDA integrin alpha4-beta7 complex
GO:0043113 IMP receptor clustering
GO:0043235 IDA receptor complex
GO:0046872 IEA metal ion binding
GO:0050776 TAS regulation of immune response
GO:0050839 IMP cell adhesion molecule binding
GO:0050900 IEA leukocyte migration
GO:0050901 IMP leukocyte tethering or rolling
GO:0070062 IDA extracellular vesicular exosome
GO:0072678 IEA T cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044318 itgb7 integrin, beta 7 protein_coding Danio_rerio
ENSMUSG00000001281 Itgb7 integrin beta 7 protein_coding Mus_musculus

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