C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pellino E3 ubiquitin protein ligase family member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139946 PELI2 9606 + 14:56117814-56301526 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267460 PELI2-001 56118375-56301526 protein_coding
  ENST00000559044 PELI2-002 56117814-56290344 protein_coding
  ENST00000561019 PELI2-003 56119109-56290293 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000267460ENST00000561019
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000267460 1.816±0.00 1.782±0.00 0.866±0.53 1.904±0.33 1.626±0.78 0.415±0.10 0.453±0.05 0.668±0.43 2.248±0.36 0.869±0.31 1.554±0.84 4.391±0.42
ENST00000561019 N/A N/A 2.603±0.00 6.172±0.00 5.047±0.00 1.225±0.00 1.113±0.00 N/A N/A 5.363±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000604 CIL_000604_0002 CGP 14:55559072-56301526
CIL_000601 CIL_000601_0002 CGP 14:56117814-56650606

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0008063 IEA Toll signaling pathway
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043123 TAS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410 IDA positive regulation of MAPK cascade
GO:0045087 TAS innate immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029045 peli2 pellino homolog 2 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000021846 Peli2 pellino 2 protein_coding Mus_musculus

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