C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual oxidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140279 DUOX2 9606 - 15:45092650-45114344 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000389039 DUOX2-001 45092650-45114344 protein_coding
  ENST00000558383 DUOX2-002 45099029-45113454 retained_intron
  ENST00000558416 DUOX2-003 45100843-45101857 retained_intron
  ENST00000560797 DUOX2-004 45099817-45100413 retained_intron
  ENST00000603300 DUOX2-201 45092655-45114161 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastKidneyLiverOvaryENST00000389039ENST00000558383ENST00000603300
Transcript ID Breast Kidney Liver Ovary
ENST00000389039 N/A N/A 0.785±0.00 2.149±0.00
ENST00000558383 N/A N/A N/A 0.531±0.00
ENST00000603300 0.661±0.00 0.422±0.00 N/A 2.100±0.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OV CIL_0003OV_0001 CGP 15:45023104-45114344
CIL_0004DP CIL_0004DP_0001 CGP 15:45092650-45118421

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004601 IEA peroxidase activity
GO:0005509 IEA calcium ion binding
GO:0005886 IEA plasma membrane
GO:0006590 IEA thyroid hormone generation
GO:0006979 IEA response to oxidative stress
GO:0009566 IEA fertilization
GO:0009615 IDA response to virus
GO:0016021 IEA integral component of membrane
GO:0016174 IEA NAD(P)H oxidase activity
GO:0016491 IEA oxidoreductase activity
GO:0019221 ISS cytokine-mediated signaling pathway
GO:0020037 IEA heme binding
GO:0030282 IEA bone mineralization
GO:0030878 IEA thyroid gland development
GO:0035264 IEA multicellular organism growth
GO:0042335 ISS cuticle development
GO:0042403 IEA thyroid hormone metabolic process
GO:0042445 IEA hormone metabolic process
GO:0042446 IEA hormone biosynthetic process
GO:0042744 IEA hydrogen peroxide catabolic process
GO:0048839 IEA inner ear development
GO:0048855 IEA adenohypophysis morphogenesis
GO:0051591 ISS response to cAMP
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062632 duox dual oxidase protein_coding Danio_rerio
ENSMUSG00000068452 Duox2 dual oxidase 2 protein_coding Mus_musculus

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