C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual oxidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000068452 Duox2 10090 - 2:122279247-122298165 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000053734 Duox2-001 122279247-122298165 protein_coding
  ENSMUST00000155820 Duox2-002 122282708-122285569 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000053734ENSMUST00000155820
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000053734 0.091±0.07 0.026±0.01 0.215±0.00 0.019±0.01 0.182±0.03 12.080±5.92 0.061±0.05 0.025±0.01 0.010±0.01 0.131±0.00 0.019±0.01 0.277±0.19 0.025±0.02 0.022±0.01
ENSMUST00000155820 0.048±0.00 0.010±0.00 N/A 0.008±0.00 0.210±0.00 N/A N/A N/A 0.046±0.00 N/A 0.058±0.02 0.332±0.11 0.032±0.01 0.049±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OV CIL_0003OV_0002 CGP 2:122234749-122298165
CIL_0004DP CIL_0004DP_0002 CGP 2:122279247-122302885

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004601 IEA peroxidase activity
GO:0006590 IEA thyroid hormone generation
GO:0006979 IEA response to oxidative stress
GO:0009566 IMP fertilization
GO:0009615 IEA response to virus
GO:0016021 IEA integral component of membrane
GO:0016174 IEA NAD(P)H oxidase activity
GO:0020037 IEA heme binding
GO:0030282 IMP bone mineralization
GO:0030878 IMP thyroid gland development
GO:0035264 IMP multicellular organism growth
GO:0042403 IMP thyroid hormone metabolic process
GO:0042445 IMP hormone metabolic process
GO:0048839 IMP inner ear development
GO:0048855 IMP adenohypophysis morphogenesis
GO:0055114 IEA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062632 duox dual oxidase protein_coding Danio_rerio
ENSG00000140279 DUOX2 dual oxidase 2 protein_coding Homo_sapiens

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