C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PIF1 5'-to-3' DNA helicase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140451 PIF1 9606 - 15:64815632-64825668 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268043 PIF1-001 64815632-64825668 protein_coding
  ENST00000333425 PIF1-002 64815632-64825668 protein_coding
  ENST00000558380 PIF1-010 64819037-64821457 retained_intron
  ENST00000558547 PIF1-011 64821067-64821419 retained_intron
  ENST00000559239 PIF1-006 64815637-64825639 protein_coding
  ENST00000559522 PIF1-007 64818010-64818824 retained_intron
  ENST00000559872 PIF1-009 64816652-64821131 retained_intron
  ENST00000560444 PIF1-004 64821590-64825625 retained_intron
  ENST00000560504 PIF1-003 64823266-64825617 retained_intron

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268043ENST00000333425ENST00000558380ENST00000559239ENST00000560444ENST00000560504
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268043 N/A N/A N/A 0.061±0.00 N/A N/A N/A N/A N/A N/A 3.105±2.52 N/A 0.972±0.00
ENST00000333425 N/A N/A 0.097±0.00 N/A N/A 0.083±0.00 N/A N/A N/A N/A 0.298±0.00 0.261±0.00 N/A
ENST00000558380 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.133±0.00 N/A N/A
ENST00000559239 N/A 0.569±0.00 N/A 0.281±0.09 0.221±0.00 0.049±0.00 N/A 0.036±0.00 0.068±0.00 N/A 0.077±0.00 0.468±0.23 N/A
ENST00000560444 0.348±0.00 0.920±0.00 0.383±0.00 0.270±0.00 0.471±0.00 0.164±0.00 0.579±0.00 0.017±0.00 0.210±0.00 0.160±0.00 0.222±0.00 N/A 0.440±0.14
ENST00000560504 0.183±0.00 0.738±0.00 0.183±0.00 N/A N/A 0.389±0.00 0.605±0.00 N/A 0.896±0.00 N/A N/A N/A 0.408±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RY CIL_0007RY_0001 VISTA 15:64785331-65389080

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000002 IEA mitochondrial genome maintenance
GO:0000287 IDA magnesium ion binding
GO:0000723 IEA telomere maintenance
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0003678 IEA DNA helicase activity
GO:0004386 IEA helicase activity
GO:0005524 IDA:IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0006200 IDA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0010521 IEA telomerase inhibitor activity
GO:0017116 IDA single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0032204 IDA regulation of telomere maintenance
GO:0032211 IEA negative regulation of telomere maintenance via telomerase
GO:0032508 IEA DNA duplex unwinding
GO:0033682 IDA ATP-dependent 5'-3' DNA/RNA helicase activity
GO:0042162 IDA telomeric DNA binding
GO:0043141 IDA ATP-dependent 5'-3' DNA helicase activity
GO:0051880 IEA G-quadruplex DNA binding
GO:0051974 IDA negative regulation of telomerase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020289 pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000041064 Pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) protein_coding Mus_musculus

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