C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041064 Pif1 10090 + 9:65587160-65595967 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047099 Pif1-001 65587205-65595967 protein_coding
  ENSMUST00000131483 Pif1-004 65587221-65595967 protein_coding
  ENSMUST00000134538 Pif1-002 65587160-65595964 protein_coding
  ENSMUST00000136205 Pif1-008 65587182-65587837 protein_coding
  ENSMUST00000141046 Pif1-007 65587226-65588280 protein_coding
  ENSMUST00000152529 Pif1-005 65587213-65595967 retained_intron
  ENSMUST00000152885 Pif1-006 65587205-65590492 retained_intron
  ENSMUST00000154970 Pif1-003 65587193-65595962 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047099ENSMUST00000131483ENSMUST00000134538ENSMUST00000136205ENSMUST00000141046ENSMUST00000152529ENSMUST00000152885ENSMUST00000154970
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047099 0.090±0.04 N/A 0.061±0.00 0.588±0.00 N/A 0.444±0.06 0.018±0.00 0.051±0.00 1.705±0.00 N/A N/A 0.356±0.05 0.757±0.78 0.143±0.06
ENSMUST00000131483 0.042±0.00 0.101±0.03 0.036±0.00 0.506±0.43 0.146±0.02 0.575±0.16 0.026±0.02 0.082±0.01 2.349±0.94 0.082±0.07 N/A 0.681±0.34 0.283±0.29 N/A
ENSMUST00000134538 0.127±0.03 N/A N/A 0.417±0.04 0.240±0.03 0.531±0.26 N/A N/A 1.891±1.36 N/A N/A 0.914±0.09 1.062±0.74 N/A
ENSMUST00000136205 N/A N/A N/A N/A 1.361±0.00 N/A N/A N/A N/A N/A N/A N/A 0.287±0.00 1.284±0.00
ENSMUST00000141046 N/A 0.430±0.22 N/A N/A 0.377±0.10 1.340±0.13 0.153±0.05 0.052±0.00 N/A 0.289±0.12 N/A 1.238±0.67 N/A 0.301±0.00
ENSMUST00000152529 0.019±0.00 0.086±0.00 N/A N/A N/A 0.266±0.00 N/A 0.087±0.03 0.043±0.01 0.044±0.00 N/A 0.239±0.06 0.020±0.00 N/A
ENSMUST00000152885 0.159±0.00 0.081±0.05 N/A 0.025±0.00 0.080±0.01 0.187±0.00 N/A 0.054±0.02 0.897±0.89 0.043±0.02 0.022±0.01 0.334±0.12 0.194±0.15 0.104±0.00
ENSMUST00000154970 N/A N/A N/A 0.501±0.16 N/A 0.197±0.00 N/A 0.083±0.00 1.513±0.76 N/A 0.027±0.00 0.395±0.15 0.505±0.06 0.115±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RY CIL_0007RY_0002 VISTA 9:65081642-65684657
CIL_0008H0 CIL_0008H0_0002 VISTA 9:65525988-66127110

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000002 IEA mitochondrial genome maintenance
GO:0000287 IEA magnesium ion binding
GO:0000723 IEA telomere maintenance
GO:0000784 IEA nuclear chromosome, telomeric region
GO:0003678 IEA DNA helicase activity
GO:0005524 IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0010521 IEA telomerase inhibitor activity
GO:0017116 IEA single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0032204 IEA regulation of telomere maintenance
GO:0032211 IEA negative regulation of telomere maintenance via telomerase
GO:0032508 IEA DNA duplex unwinding
GO:0033682 IEA ATP-dependent 5'-3' DNA/RNA helicase activity
GO:0042162 IEA telomeric DNA binding
GO:0043141 IEA ATP-dependent 5'-3' DNA helicase activity
GO:0051880 IEA G-quadruplex DNA binding
GO:0051974 IEA negative regulation of telomerase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020289 pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000140451 PIF1 PIF1 5'-to-3' DNA helicase protein_coding Homo_sapiens

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