C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphoinositide-3-kinase, regulatory subunit 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141506 PIK3R5 9606 - 17:8878911-8965712 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269300 PIK3R5-002 8878911-8965703 nonsense_mediated_decay
  ENST00000447110 PIK3R5-201 8878917-8965712 protein_coding
  ENST00000577214 PIK3R5-013 8880651-8887270 retained_intron
  ENST00000577981 PIK3R5-007 8890819-8965712 processed_transcript
  ENST00000578457 PIK3R5-005 8888741-8911512 processed_transcript
  ENST00000578515 PIK3R5-003 8880639-8965707 retained_intron
  ENST00000578743 PIK3R5-011 8880641-8885086 processed_transcript
  ENST00000580959 PIK3R5-006 8888741-8965615 processed_transcript
  ENST00000581552 PIK3R5-001 8880096-8912517 protein_coding
  ENST00000581895 PIK3R5-015 8909144-8911988 protein_coding
  ENST00000583039 PIK3R5-010 8887427-8888513 retained_intron
  ENST00000583222 PIK3R5-016 8915700-8965707 processed_transcript
  ENST00000583810 PIK3R5-012 8880578-8882508 retained_intron
  ENST00000583812 PIK3R5-009 8888823-8893650 processed_transcript
  ENST00000584456 PIK3R5-008 8888638-8893908 processed_transcript
  ENST00000584803 PIK3R5-004 8880639-8911507 protein_coding
  ENST00000585260 PIK3R5-014 8880464-8881869 protein_coding
  ENST00000611902 PIK3R5-202 8878919-8965712 protein_coding
  ENST00000616147 PIK3R5-203 8878919-8965712 protein_coding
  ENST00000623421 PIK3R5-204 8878919-8965712 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000269300ENST00000447110ENST00000577214ENST00000581895ENST00000583039ENST00000583222ENST00000584803ENST00000611902ENST00000616147ENST00000623421
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000269300 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.190±0.00
ENST00000447110 N/A N/A N/A 0.135±0.00 0.819±0.00 N/A N/A 0.316±0.00 1.080±0.31 N/A 0.281±0.00 1.027±0.33 N/A
ENST00000577214 N/A N/A N/A N/A N/A N/A 0.230±0.00 1.264±0.00 N/A 0.073±0.00 1.544±0.00 N/A N/A
ENST00000581895 N/A N/A 0.930±0.00 N/A N/A 1.435±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000583039 N/A N/A N/A 0.767±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000583222 N/A N/A N/A N/A N/A N/A 0.101±0.00 N/A N/A N/A N/A N/A N/A
ENST00000584803 N/A N/A N/A N/A 0.758±0.00 N/A N/A 0.392±0.00 1.049±0.00 N/A N/A N/A N/A
ENST00000611902 N/A 1.447±0.00 0.057±0.00 N/A N/A N/A 0.164±0.00 N/A N/A N/A N/A N/A 0.386±0.00
ENST00000616147 N/A 1.507±0.00 N/A N/A 0.265±0.00 0.328±0.00 0.232±0.00 N/A N/A N/A 0.212±0.00 N/A N/A
ENST00000623421 1.077±0.00 2.526±0.00 N/A 0.100±0.00 0.189±0.00 0.166±0.00 N/A N/A N/A 0.085±0.00 N/A N/A 0.383±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AZ CIL_0009AZ_0001 VISTA 17:8380027-8982000
CIL_00088C CIL_00088C_0001 VISTA 17:8397056-8997791
CIL_0001LK CIL_0001LK_0002 CGP 17:8878911-9244000

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0005942 IEA phosphatidylinositol 3-kinase complex
GO:0005944 IEA phosphatidylinositol 3-kinase complex, class IB
GO:0006644 TAS phospholipid metabolic process
GO:0006661 TAS phosphatidylinositol biosynthetic process
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0007596 TAS blood coagulation
GO:0008219 IEA cell death
GO:0014065 ISS phosphatidylinositol 3-kinase signaling
GO:0016020 ISS membrane
GO:0030168 TAS platelet activation
GO:0031683 ISS G-protein beta/gamma-subunit complex binding
GO:0043406 ISS positive regulation of MAP kinase activity
GO:0043551 IEA regulation of phosphatidylinositol 3-kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0046935 IEA 1-phosphatidylinositol-3-kinase regulator activity
GO:0051897 ISS positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079451 pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 protein_coding Danio_rerio
ENSMUSG00000020901 Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5, p101 protein_coding Mus_musculus

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