C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho GDP dissociation inhibitor (GDI) alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141522 ARHGDIA 9606 - 17:81867721-81871406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269321 ARHGDIA-001 81867721-81871406 protein_coding
  ENST00000400721 ARHGDIA-002 81867897-81871376 protein_coding
  ENST00000541078 ARHGDIA-012 81868340-81870974 protein_coding
  ENST00000578351 ARHGDIA-004 81869049-81871326 nonsense_mediated_decay
  ENST00000579121 ARHGDIA-013 81868506-81870664 protein_coding
  ENST00000580033 ARHGDIA-011 81868922-81871325 nonsense_mediated_decay
  ENST00000580685 ARHGDIA-015 81868366-81870006 protein_coding
  ENST00000581876 ARHGDIA-016 81868611-81871324 protein_coding
  ENST00000582309 ARHGDIA-014 81869523-81870265 retained_intron
  ENST00000582520 ARHGDIA-018 81867721-81868630 processed_transcript
  ENST00000582984 ARHGDIA-007 81868870-81871337 retained_intron
  ENST00000583111 ARHGDIA-010 81869166-81871329 retained_intron
  ENST00000583499 ARHGDIA-008 81869438-81871337 retained_intron
  ENST00000583791 ARHGDIA-017 81869004-81869451 retained_intron
  ENST00000583868 ARHGDIA-006 81868631-81871337 protein_coding
  ENST00000584397 ARHGDIA-005 81869302-81871378 retained_intron
  ENST00000584461 ARHGDIA-009 81868260-81871329 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000269321ENST00000400721ENST00000578351ENST00000579121ENST00000580685ENST00000583111ENST00000584397ENST00000584461
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000269321 169.923±0.00 171.536±0.00 1.608±0.00 51.659±44.60 55.392±50.30 53.492±45.63 20.096±18.68 58.564±51.36 26.273±22.29 111.175±107.49 29.634±26.35 103.915±87.73 198.690±93.42 63.158±36.04
ENST00000400721 40.294±0.00 52.169±0.00 1.061±0.00 N/A 24.188±0.00 30.862±0.00 N/A N/A N/A N/A N/A 1.703±0.00 N/A 22.423±0.00
ENST00000578351 N/A N/A N/A N/A 9.091±0.00 N/A 1.450±0.00 10.356±0.00 4.066±0.00 N/A N/A N/A N/A N/A
ENST00000579121 N/A N/A N/A N/A N/A N/A N/A N/A 2.287±0.00 N/A N/A 3.033±0.00 N/A N/A
ENST00000580685 N/A N/A 1.795±0.00 N/A 5.305±0.00 5.312±0.00 N/A N/A N/A N/A N/A 47.270±0.00 92.680±0.00 23.990±0.00
ENST00000583111 N/A N/A N/A N/A N/A N/A 1.065±0.00 N/A N/A 8.351±0.00 N/A N/A N/A N/A
ENST00000584397 N/A N/A N/A N/A N/A N/A N/A N/A 3.436±0.00 N/A N/A N/A N/A N/A
ENST00000584461 56.054±0.00 N/A N/A N/A 32.394±0.00 N/A N/A 58.689±0.00 N/A N/A N/A 21.377±0.00 N/A 14.394±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004M1 CIL_0004M1_0001 CGP 17:81843159-81871406
CIL_0004M2 CIL_0004M2_0001 CGP 17:81867721-81891586

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001772 IEA immunological synapse
GO:0005094 IEA Rho GDP-dissociation inhibitor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 TAS cytoskeleton
GO:0006928 TAS cellular component movement
GO:0007162 TAS negative regulation of cell adhesion
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 IEA Rho protein signal transduction
GO:0030336 IEA negative regulation of cell migration
GO:0032880 IEA regulation of protein localization
GO:0043066 TAS negative regulation of apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis
GO:0050772 TAS positive regulation of axonogenesis
GO:0050790 IEA regulation of catalytic activity
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0071526 ISS semaphorin-plexin signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043795 arhgdia Rho GDP dissociation inhibitor (GDI) alpha protein_coding Danio_rerio
ENSMUSG00000025132 Arhgdia Rho GDP dissociation inhibitor (GDI) alpha protein_coding Mus_musculus

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