C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cadherin, EGF LAG seven-pass G-type receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143126 CELSR2 9606 + 1:109250019-109275750 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000271332 CELSR2-001 109250019-109275750 protein_coding
  ENST00000459940 CELSR2-005 109265269-109266439 processed_transcript
  ENST00000489018 CELSR2-002 109269727-109274309 processed_transcript
  ENST00000498157 CELSR2-003 109270824-109275607 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000271332ENST00000489018ENST00000498157
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000271332 0.437±0.00 N/A 0.997±0.00 13.209±11.13 1.757±0.00 0.587±0.44 1.020±0.91 0.869±0.86 0.377±0.05 0.416±0.00 1.473±1.15 1.238±1.16 0.328±0.19 2.704±1.92
ENST00000489018 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.565±0.00 0.372±0.00 N/A
ENST00000498157 0.235±0.00 0.239±0.00 N/A 9.625±0.00 N/A 1.391±0.00 N/A 4.858±0.00 1.856±0.00 0.548±0.00 N/A 0.941±0.00 0.271±0.00 7.870±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098X CIL_00098X_0001 VISTA 1:108953074-109556228
CIL_00099A CIL_00099A_0001 VISTA 1:108974252-109576283

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0003341 IEA cilium movement
GO:0004888 IEA transmembrane signaling receptor activity
GO:0004930 NAS:IEA G-protein coupled receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0007156 ISS:IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007186 NAS:IEA G-protein coupled receptor signaling pathway
GO:0007218 IEA neuropeptide signaling pathway
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0016055 ISS Wnt signaling pathway
GO:0021591 IEA ventricular system development
GO:0021999 ISS neural plate anterior/posterior regionalization
GO:0022407 ISS regulation of cell-cell adhesion
GO:0032880 IEA regulation of protein localization
GO:0033326 IEA cerebrospinal fluid secretion
GO:0042384 IEA cilium assembly
GO:0048813 ISS dendrite morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019726 celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 protein_coding Danio_rerio
ENSDARG00000088231 CELSR2 (2 of 2) cadherin, EGF LAG seven-pass G-type receptor 2 protein_coding Danio_rerio
ENSMUSG00000068740 Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) protein_coding Mus_musculus

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