C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Fc fragment of IgG, low affinity IIa, receptor (CD32)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143226 FCGR2A 9606 + 1:161505430-161524013 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000271450 FCGR2A-001 161505430-161519568 protein_coding
  ENST00000367972 FCGR2A-002 161505430-161518558 protein_coding
  ENST00000459885 FCGR2A-017 161513898-161519967 protein_coding
  ENST00000461298 FCGR2A-014 161513377-161518590 processed_transcript
  ENST00000467525 FCGR2A-018 161506333-161524013 nonsense_mediated_decay
  ENST00000467654 FCGR2A-007 161505446-161510350 retained_intron
  ENST00000471026 FCGR2A-011 161506651-161518355 processed_transcript
  ENST00000473080 FCGR2A-008 161505453-161506368 retained_intron
  ENST00000482233 FCGR2A-009 161505868-161506640 retained_intron
  ENST00000483665 FCGR2A-020 161505457-161518565 nonsense_mediated_decay
  ENST00000486608 FCGR2A-015 161514620-161518603 processed_transcript
  ENST00000491841 FCGR2A-016 161517975-161523099 processed_transcript
  ENST00000497474 FCGR2A-019 161505459-161506449 retained_intron
  ENST00000536731 FCGR2A-021 161505457-161509899 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000271450ENST00000471026
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000271450 26.318±0.00 6.747±0.00 1.679±0.00 4.111±2.94 10.097±6.35 2.581±1.58 2.921±0.00 4.366±2.46 3.931±1.43 24.823±6.56 1.223±0.25 5.388±2.75 24.972±7.82 1.478±0.73
ENST00000471026 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.503±0.00 N/A 1.661±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0016021 IEA integral component of membrane
GO:0019864 IEA IgG binding
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026656 Fcgr2b Fc receptor, IgG, low affinity IIb protein_coding Mus_musculus
ENSMUSG00000059498 Fcgr3 Fc receptor, IgG, low affinity III protein_coding Mus_musculus

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