C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 21
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143258 USP21 9606 + 1:161159450-161165723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289865 USP21-001 161159479-161165723 protein_coding
  ENST00000368001 USP21-002 161159537-161165723 protein_coding
  ENST00000368002 USP21-201 161159464-161165714 protein_coding
  ENST00000479344 USP21-005 161159521-161160992 protein_coding
  ENST00000482385 USP21-008 161162624-161164822 retained_intron
  ENST00000485277 USP21-009 161163879-161165505 retained_intron
  ENST00000486299 USP21-006 161160744-161162680 processed_transcript
  ENST00000487163 USP21-003 161161363-161165723 retained_intron
  ENST00000492950 USP21-004 161159450-161162368 protein_coding
  ENST00000493054 USP21-007 161163555-161165627 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000289865ENST00000368001ENST00000368002ENST00000482385ENST00000485277ENST00000487163ENST00000492950ENST00000493054
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000289865 2.469±0.00 N/A N/A 2.550±0.00 3.536±0.00 1.643±1.43 2.055±0.00 0.419±0.00 6.356±0.00 3.058±0.00 12.499±7.57 5.992±2.24 6.744±0.00
ENST00000368001 N/A N/A N/A 0.819±0.00 0.241±0.00 N/A 0.151±0.00 N/A N/A 0.834±0.00 1.835±0.00 1.345±0.00 N/A
ENST00000368002 N/A N/A N/A N/A 2.829±0.00 N/A 4.111±0.00 0.597±0.00 2.413±0.00 3.028±0.00 2.624±0.00 2.860±0.00 7.691±0.00
ENST00000482385 N/A N/A N/A N/A N/A N/A 0.365±0.00 N/A N/A N/A 6.365±0.00 3.857±0.00 8.029±0.00
ENST00000485277 1.722±0.00 1.336±0.00 3.057±0.00 0.438±0.00 N/A N/A N/A N/A N/A 2.133±1.06 N/A N/A 4.609±0.00
ENST00000487163 N/A N/A N/A 0.117±0.00 N/A 0.045±0.00 N/A N/A N/A N/A N/A N/A 3.121±0.00
ENST00000492950 N/A N/A N/A N/A N/A N/A N/A 1.249±0.00 N/A N/A 0.858±0.00 N/A 4.344±0.00
ENST00000493054 N/A 3.421±0.00 N/A N/A 3.721±0.00 0.123±0.00 6.795±0.00 1.492±0.00 1.078±0.00 4.448±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003713 ISS transcription coactivator activity
GO:0004221 ISS ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005575 ND cellular_component
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0008234 ISS cysteine-type peptidase activity
GO:0016578 ISS histone deubiquitination
GO:0019784 IDA NEDD8-specific protease activity
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094280 USP21 ubiquitin specific peptidase 21 protein_coding Danio_rerio
ENSMUSG00000053483 Usp21 ubiquitin specific peptidase 21 protein_coding Mus_musculus

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