C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAR-related orphan receptor C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143365 RORC 9606 - 1:151806071-151831872 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000318247 RORC-001 151806957-151831872 protein_coding
  ENST00000356728 RORC-002 151806071-151826091 protein_coding
  ENST00000480719 RORC-003 151806958-151814789 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000318247ENST00000356728ENST00000480719
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000318247 0.125±0.00 N/A N/A 0.055±0.00 N/A N/A N/A N/A N/A N/A N/A 0.453±0.15 0.076±0.00 N/A
ENST00000356728 0.120±0.00 0.548±0.00 2.205±0.00 0.089±0.04 1.977±1.50 1.980±0.18 1.656±0.99 15.552±2.46 10.409±10.07 3.507±0.55 26.050±18.14 1.075±0.51 0.094±0.04 4.621±0.33
ENST00000480719 0.019±0.00 N/A 1.050±0.00 0.013±0.00 0.229±0.00 0.348±0.17 N/A 2.045±0.21 0.084±0.00 0.430±0.11 N/A 0.052±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001223 IEA transcription coactivator binding
GO:0003677 ISS DNA binding
GO:0003700 ISS:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IEA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0006805 ISS xenobiotic metabolic process
GO:0008142 IDA oxysterol binding
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0010906 ISS regulation of glucose metabolic process
GO:0019218 ISS regulation of steroid metabolic process
GO:0030154 IEA cell differentiation
GO:0030522 IEA intracellular receptor signaling pathway
GO:0032922 ISS circadian regulation of gene expression
GO:0033077 IEA T cell differentiation in thymus
GO:0036315 IDA cellular response to sterol
GO:0042093 ISS T-helper cell differentiation
GO:0042753 ISS positive regulation of circadian rhythm
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0045586 IEA regulation of gamma-delta T cell differentiation
GO:0045598 ISS regulation of fat cell differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046632 IEA alpha-beta T cell differentiation
GO:0048535 ISS lymph node development
GO:0048537 IEA mucosal-associated lymphoid tissue development
GO:0048541 ISS Peyer's patch development
GO:0060612 ISS adipose tissue development
GO:0060850 ISS regulation of transcription involved in cell fate commitment
GO:0070244 ISS negative regulation of thymocyte apoptotic process
GO:0072539 ISS T-helper 17 cell differentiation
GO:0098531 IDA direct ligand regulated sequence-specific DNA binding transcription factor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087195 RORC RAR-related orphan receptor C protein_coding Danio_rerio
ENSMUSG00000028150 Rorc RAR-related orphan receptor gamma protein_coding Mus_musculus

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