C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143507 DUSP10 9606 - 1:221701424-221742176 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366899 DUSP10-001 221701424-221742176 protein_coding
  ENST00000468085 DUSP10-003 221701483-221736900 nonsense_mediated_decay
  ENST00000477026 DUSP10-002 221702150-221742089 nonsense_mediated_decay
  ENST00000494642 DUSP10-004 221702427-221711816 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000366899ENST00000468085ENST00000477026ENST00000494642
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000366899 1.282±0.00 2.112±0.00 0.251±0.00 1.777±0.54 1.763±1.33 0.616±0.39 0.641±0.04 1.441±1.18 2.308±1.18 2.430±0.00 2.156±0.02 2.345±0.74 1.113±0.26 1.959±0.45
ENST00000468085 N/A N/A 0.208±0.00 N/A 0.887±0.00 0.568±0.00 N/A 0.422±0.00 1.179±0.64 N/A N/A 0.882±0.00 0.920±0.00 N/A
ENST00000477026 0.730±0.00 N/A N/A 2.135±0.00 1.636±0.62 0.913±0.05 N/A N/A N/A 1.669±0.00 1.278±0.00 1.996±0.00 0.874±0.30 3.883±0.66
ENST00000494642 N/A N/A N/A 0.786±0.00 N/A 1.433±0.00 N/A N/A N/A N/A N/A 2.077±0.00 N/A 2.190±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007Q6 CIL_0007Q6_0001 VISTA 1:221433436-222033436
CIL_0009C7 CIL_0009C7_0001 VISTA 1:221433451-222035140

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 IDA inactivation of MAPK activity
GO:0002819 IEA regulation of adaptive immune response
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0006470 IDA:IEA protein dephosphorylation
GO:0006950 TAS response to stress
GO:0007254 TAS JNK cascade
GO:0008138 IBA:IEA protein tyrosine/serine/threonine phosphatase activity
GO:0010033 IEA response to organic substance
GO:0016311 IEA dephosphorylation
GO:0016791 IDA:IEA phosphatase activity
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0032496 IEA response to lipopolysaccharide
GO:0032873 IEA negative regulation of stress-activated MAPK cascade
GO:0033549 IDA MAP kinase phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043508 IBA negative regulation of JUN kinase activity
GO:0044387 IEA negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045088 IEA regulation of innate immune response
GO:0046329 IBA negative regulation of JNK cascade
GO:0048709 IEA oligodendrocyte differentiation
GO:0048715 IEA negative regulation of oligodendrocyte differentiation
GO:0060266 IEA negative regulation of respiratory burst involved in inflammatory response
GO:0090335 IEA regulation of brown fat cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052465 DUSP10 dual specificity phosphatase 10 protein_coding Danio_rerio
ENSMUSG00000039384 Dusp10 dual specificity phosphatase 10 protein_coding Mus_musculus

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