C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dual specificity phosphatase 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039384 Dusp10 10090 + 1:184013302-184075636 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048655 Dusp10-001 184034381-184075636 protein_coding
  ENSMUST00000139839 Dusp10-002 184013302-184037274 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048655ENSMUST00000139839
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048655 6.046±1.49 2.827±0.61 4.163±0.77 1.635±0.87 8.590±4.52 3.796±0.68 3.283±0.99 1.421±0.31 2.245±0.30 3.217±0.38 10.329±4.22 3.961±2.02 1.333±0.75 6.633±3.32
ENSMUST00000139839 N/A N/A N/A N/A 7.451±0.00 5.704±0.00 N/A 0.923±0.00 1.644±0.42 N/A N/A 8.828±5.59 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009C7 CIL_0009C7_0002 VISTA 1:183741270-184342762
CIL_0007Q6 CIL_0007Q6_0002 VISTA 1:183741272-184341272

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000188 ISS inactivation of MAPK activity
GO:0002819 IMP regulation of adaptive immune response
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0006470 IBA:ISS protein dephosphorylation
GO:0008138 IBA protein tyrosine/serine/threonine phosphatase activity
GO:0010033 IEA response to organic substance
GO:0017017 IEA MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0032496 IMP response to lipopolysaccharide
GO:0032873 IMP negative regulation of stress-activated MAPK cascade
GO:0033549 ISS MAP kinase phosphatase activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0043508 IMP negative regulation of JUN kinase activity
GO:0044387 IDA negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0045088 IMP regulation of innate immune response
GO:0046329 IMP negative regulation of JNK cascade
GO:0048709 IMP oligodendrocyte differentiation
GO:0048715 IEA negative regulation of oligodendrocyte differentiation
GO:0060266 IMP negative regulation of respiratory burst involved in inflammatory response
GO:0090335 IDA regulation of brown fat cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052465 DUSP10 dual specificity phosphatase 10 protein_coding Danio_rerio
ENSG00000143507 DUSP10 dual specificity phosphatase 10 protein_coding Homo_sapiens

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