C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hyperpolarization activated cyclic nucleotide-gated potassium channel 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143630 HCN3 9606 + 1:155277583-155289848 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368358 HCN3-001 155277583-155289848 protein_coding
  ENST00000467204 HCN3-003 155282538-155287903 processed_transcript
  ENST00000492035 HCN3-004 155288604-155289518 processed_transcript
  ENST00000496230 HCN3-002 155277699-155289847 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368358ENST00000467204ENST00000492035ENST00000496230
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368358 N/A 0.406±0.06 0.237±0.00 N/A 0.013±0.00 1.638±0.00 0.156±0.00 0.095±0.00 N/A 0.846±0.00 0.328±0.03 0.533±0.00
ENST00000467204 N/A N/A 0.549±0.00 0.405±0.00 N/A N/A N/A N/A N/A N/A 0.317±0.00 N/A
ENST00000492035 0.341±0.00 N/A N/A N/A N/A N/A N/A 0.738±0.15 N/A 1.244±0.00 0.320±0.00 N/A
ENST00000496230 N/A N/A N/A N/A 0.076±0.04 N/A N/A 0.061±0.00 0.065±0.00 N/A 0.149±0.00 0.365±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005248 IMP voltage-gated sodium channel activity
GO:0005249 IBA voltage-gated potassium channel activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0007268 TAS synaptic transmission
GO:0016020 IEA membrane
GO:0030552 IEA cAMP binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IMP sodium ion transmembrane transport
GO:0042391 IBA regulation of membrane potential
GO:0055085 IEA transmembrane transport
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027192 hcn3 hyperpolarization activated cyclic nucleotide-gated potassium channel 3 protein_coding Danio_rerio
ENSDARG00000076615 HCN3 (2 of 2) hyperpolarization activated cyclic nucleotide-gated potassium channel 3 protein_coding Danio_rerio
ENSMUSG00000028051 Hcn3 hyperpolarization-activated, cyclic nucleotide-gated K+ 3 protein_coding Mus_musculus

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