C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hyperpolarization activated cyclic nucleotide-gated potassium channel 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368358 HCN3-001 ENSG00000143630 9606 + 1:155277583-155289848 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000368358
Transcript ID Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000368358 0.406±0.06 0.237±0.00 0.013±0.00 1.638±0.00 0.156±0.00 0.095±0.00 0.846±0.00 0.328±0.03 0.533±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005248 IMP voltage-gated sodium channel activity
GO:0005249 IBA voltage-gated potassium channel activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0007268 TAS synaptic transmission
GO:0016020 IEA membrane
GO:0030552 IEA cAMP binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IMP sodium ion transmembrane transport
GO:0042391 IBA regulation of membrane potential
GO:0055085 IEA transmembrane transport
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029686 Hcn3-001 protein_coding Mus_musculus 0 2833
ENSMUST00000034889 Hcn4-201 protein_coding Mus_musculus 0 1166
ENSMUST00000020581 Hcn2-201 protein_coding Mus_musculus 0 1090
ENSMUST00000099513 Hcn2-001 protein_coding Mus_musculus 0 1090
ENSMUST00000132156 Hcn3-003 retained_intron Mus_musculus 0 1031
ENSDART00000093300 hcn4-201 protein_coding Danio_rerio 0 928
ENSDART00000136140 hcn4-001 protein_coding Danio_rerio 0 928
ENSDART00000113932 HCN1-201 protein_coding Danio_rerio 0 787
ENSDART00000136390 hcn2b-001 protein_coding Danio_rerio 0 758
ENSDART00000151713 hcn3-201 protein_coding Danio_rerio 0 726
ENSDART00000039325 hcn3-001 protein_coding Danio_rerio 0 726
ENSMUST00000127654 Hcn3-004 retained_intron Mus_musculus 0 527
ENSMUST00000133368 Hcn3-002 processed_transcript Mus_musculus 0 466

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