C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hyperpolarization-activated, cyclic nucleotide-gated K+ 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028051 Hcn3 10090 - 3:89146074-89160196 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029686 Hcn3-001 89146074-89160196 protein_coding
  ENSMUST00000127654 Hcn3-004 89148849-89151214 retained_intron
  ENSMUST00000132156 Hcn3-003 89148732-89151232 retained_intron
  ENSMUST00000133368 Hcn3-002 89151481-89159980 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029686ENSMUST00000133368
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029686 0.033±0.00 3.220±1.40 0.075±0.00 4.581±2.95 0.545±0.29 0.099±0.04 1.667±0.11 10.361±2.81 0.128±0.02 0.018±0.00 1.180±0.70 1.046±0.88 0.360±0.26
ENSMUST00000133368 N/A N/A N/A 2.696±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005249 IBA voltage-gated potassium channel activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0030552 IEA cAMP binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0042391 IBA regulation of membrane potential
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000027192 hcn3 hyperpolarization activated cyclic nucleotide-gated potassium channel 3 protein_coding Danio_rerio
ENSDARG00000076615 HCN3 (2 of 2) hyperpolarization activated cyclic nucleotide-gated potassium channel 3 protein_coding Danio_rerio
ENSG00000143630 HCN3 hyperpolarization activated cyclic nucleotide-gated potassium channel 3 protein_coding Homo_sapiens

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