C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (RNA) II (DNA directed) polypeptide D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144231 POLR2D 9606 - 2:127846266-127858157 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000272645 POLR2D-001 127846266-127858157 protein_coding
  ENST00000409698 POLR2D-003 127847841-127857949 protein_coding
  ENST00000409955 POLR2D-002 127846699-127858117 protein_coding
  ENST00000487079 POLR2D-004 127847241-127858119 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272645ENST00000409955ENST00000487079
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272645 3.403±0.00 4.004±0.00 1.917±0.00 2.206±0.70 2.293±1.22 2.639±0.55 2.021±1.12 2.376±1.05 4.044±0.00 2.287±0.41 5.708±3.01 7.064±3.40 5.266±0.19 5.099±0.00
ENST00000409955 3.584±0.00 3.271±0.00 N/A 3.936±0.00 2.437±0.00 2.020±0.00 1.827±0.00 1.819±0.13 1.823±0.64 2.111±0.00 3.500±0.00 2.724±1.66 3.706±1.00 21.405±4.89
ENST00000487079 N/A N/A N/A N/A 4.171±0.00 1.488±0.55 0.948±0.00 1.120±0.00 N/A N/A N/A 7.728±3.20 3.698±0.00 23.819±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000288 IBA nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0000932 IBA cytoplasmic mRNA processing body
GO:0003697 IBA single-stranded DNA binding
GO:0003727 IBA single-stranded RNA binding
GO:0003824 IEA catalytic activity
GO:0003899 IEA:IMP DNA-directed RNA polymerase activity
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005665 IDA DNA-directed RNA polymerase II, core complex
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006351 IEA transcription, DNA-templated
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0006367 IBA transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0031369 IBA translation initiation factor binding
GO:0031990 IBA mRNA export from nucleus in response to heat stress
GO:0034402 IBA recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex
GO:0044237 IEA cellular metabolic process
GO:0045948 IBA positive regulation of translational initiation
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076509 polr2d polymerase (RNA) II (DNA directed) polypeptide D protein_coding Danio_rerio
ENSMUSG00000024258 Polr2d polymerase (RNA) II (DNA directed) polypeptide D protein_coding Mus_musculus

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