C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: atypical chemokine receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000144648 ACKR2 9606 + 3:42804752-42887974 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273145 ACKR2-201 42819619-42867282 protein_coding
  ENST00000422265 ACKR2-001 42809476-42867283 protein_coding
  ENST00000442925 ACKR2-003 42809472-42867283 protein_coding
  ENST00000460855 ACKR2-015 42809456-42887640 processed_transcript
  ENST00000463699 ACKR2-006 42809430-42864534 processed_transcript
  ENST00000480215 ACKR2-010 42809476-42843987 processed_transcript
  ENST00000492609 ACKR2-011 42843964-42864930 protein_coding
  ENST00000493193 ACKR2-013 42856037-42865201 protein_coding
  ENST00000494619 ACKR2-012 42850966-42865013 protein_coding
  ENST00000497921 ACKR2-007 42809492-42864876 protein_coding
  ENST00000498111 ACKR2-002 42809462-42887974 processed_transcript
  ENST00000565749 ACKR2-016 42804752-42835773 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartLungMusclePlacentaENST00000273145ENST00000442925ENST00000492609
Transcript ID Adipose Breast Heart Lung Muscle Placenta
ENST00000273145 N/A N/A N/A N/A N/A 8.180±0.00
ENST00000442925 3.521±0.00 N/A 0.515±0.00 1.123±0.00 0.147±0.07 11.143±0.00
ENST00000492609 N/A 8.454±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EY CIL_0003EY_0001 CGP 3:42757177-42887974

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0004950 TAS chemokine receptor activity
GO:0005044 IMP scavenger receptor activity
GO:0005515 IEA protein binding
GO:0005768 IEA endosome
GO:0005884 IDA actin filament
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006898 IMP receptor-mediated endocytosis
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0016021 IEA integral component of membrane
GO:0016493 IEA C-C chemokine receptor activity
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0019957 IEA C-C chemokine binding
GO:0042119 IEA neutrophil activation
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000044534 Ackr2 atypical chemokine receptor 2 protein_coding Mus_musculus

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