C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: atypical chemokine receptor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000044534 Ackr2 10090 + 9:121898464-121911064 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050327 Ackr2-201 121898464-121911064 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050327
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050327 1.231±0.38 0.473±0.11 2.471±0.40 0.184±0.03 4.254±1.55 0.676±0.40 0.789±0.29 0.418±0.04 0.541±0.33 15.926±7.59 0.241±0.10 1.057±0.47 2.342±1.57 0.177±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EY CIL_0003EY_0002 CGP 9:121848560-121911064

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005044 ISS scavenger receptor activity
GO:0005515 IPI protein binding
GO:0005768 IEA endosome
GO:0005884 ISS actin filament
GO:0005886 ISS plasma membrane
GO:0006898 IEA receptor-mediated endocytosis
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0007165 IDA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016493 IDA C-C chemokine receptor activity
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0019957 IPI C-C chemokine binding
GO:0042119 IEA neutrophil activation
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000144648 ACKR2 atypical chemokine receptor 2 protein_coding Homo_sapiens

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