C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: multiple EGF-like-domains 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145794 MEGF10 9606 + 5:127290831-127465737 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000274473 MEGF10-001 127290859-127461222 protein_coding
  ENST00000418761 MEGF10-002 127290847-127424604 protein_coding
  ENST00000503335 MEGF10-004 127290831-127461222 protein_coding
  ENST00000506709 MEGF10-007 127422692-127440847 processed_transcript
  ENST00000507158 MEGF10-012 127445477-127449202 retained_intron
  ENST00000508365 MEGF10-003 127290846-127424781 protein_coding
  ENST00000510513 MEGF10-011 127444413-127445544 retained_intron
  ENST00000510828 MEGF10-009 127445252-127455562 processed_transcript
  ENST00000515002 MEGF10-006 127409592-127417669 processed_transcript
  ENST00000515622 MEGF10-013 127447628-127465737 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000274473ENST00000418761ENST00000503335ENST00000506709ENST00000507158ENST00000508365ENST00000510828ENST00000515002ENST00000515622
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000274473 N/A N/A 0.039±0.00 1.785±0.72 N/A N/A 0.003±0.00 N/A 0.001±0.00 N/A N/A N/A N/A 0.222±0.00
ENST00000418761 0.014±0.00 N/A N/A N/A N/A 0.320±0.00 0.044±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000503335 N/A 0.010±0.00 0.005±0.00 4.676±0.00 0.041±0.00 0.049±0.01 0.004±0.00 N/A 0.024±0.02 0.033±0.00 0.403±0.15 N/A 0.030±0.00 N/A
ENST00000506709 0.106±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000507158 0.070±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000508365 N/A N/A N/A N/A 0.037±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000510828 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.044±0.00 N/A N/A
ENST00000515002 N/A N/A N/A N/A 0.455±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000515622 N/A N/A N/A N/A N/A N/A 0.246±0.00 0.768±0.00 N/A 0.119±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007S2 CIL_0007S2_0001 VISTA 5:126699007-127301374
CIL_0006CT CIL_0006CT_0002 CGP 5:127042558-127465737
CIL_0000H5 CIL_0000H5_0002 CGP 5:127290831-127555089

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001891 IEA phagocytic cup
GO:0004866 IEA endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0014719 ISS skeletal muscle satellite cell activation
GO:0014816 IMP skeletal muscle satellite cell differentiation
GO:0014841 ISS skeletal muscle satellite cell proliferation
GO:0016021 IEA integral component of membrane
GO:0034109 IDA homotypic cell-cell adhesion
GO:0042995 IEA cell projection
GO:0043654 IEA recognition of apoptotic cell
GO:0048641 IMP regulation of skeletal muscle tissue development
GO:0051147 IMP regulation of muscle cell differentiation
GO:0055001 IMP muscle cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017229 megf10 multiple EGF-like-domains 10 protein_coding Danio_rerio
ENSDARG00000089574 CABZ01074435.1 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000024593 Megf10 multiple EGF-like-domains 10 protein_coding Mus_musculus

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