C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: multiple EGF-like-domains 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024593 Megf10 10090 + 18:57133090-57297467 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075770 Megf10-001 57133090-57297467 protein_coding
  ENSMUST00000139892 Megf10-002 57142786-57292728 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000075770ENSMUST00000139892
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000075770 0.028±0.01 0.175±0.08 0.080±0.04 2.161±0.51 0.045±0.02 0.137±0.06 0.086±0.05 0.014±0.01 0.014±0.00 0.093±0.04 0.031±0.00 1.929±0.76 0.029±0.03 0.046±0.02
ENSMUST00000139892 0.047±0.03 0.219±0.11 N/A N/A 0.051±0.03 0.110±0.05 0.113±0.01 0.034±0.00 0.030±0.00 0.063±0.04 0.064±0.00 3.274±0.89 0.008±0.00 0.088±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007S2 CIL_0007S2_0002 VISTA 18:56596918-57198991
CIL_0006CT CIL_0006CT_0003 CGP 18:56955833-57297467
CIL_0000H5 CIL_0000H5_0003 CGP 18:57133090-57392719

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001891 IDA phagocytic cup
GO:0003674 ND molecular_function
GO:0014719 IMP skeletal muscle satellite cell activation
GO:0014816 IMP skeletal muscle satellite cell differentiation
GO:0014841 IDA skeletal muscle satellite cell proliferation
GO:0016021 IEA integral component of membrane
GO:0034109 ISS homotypic cell-cell adhesion
GO:0042995 IEA cell projection
GO:0043654 IDA recognition of apoptotic cell
GO:0048641 IEA regulation of skeletal muscle tissue development
GO:0051147 ISS regulation of muscle cell differentiation
GO:0055001 ISS muscle cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017229 megf10 multiple EGF-like-domains 10 protein_coding Danio_rerio
ENSDARG00000089574 CABZ01074435.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000145794 MEGF10 multiple EGF-like-domains 10 protein_coding Homo_sapiens

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