C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-cell lymphoma invasion and metastasis 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146426 TIAM2 9606 + 6:154832697-155257723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000275246 TIAM2-010 155216637-155257220 protein_coding
  ENST00000318981 TIAM2-201 155090289-155257723 protein_coding
  ENST00000360366 TIAM2-009 155129172-155257662 protein_coding
  ENST00000431620 TIAM2-016 155013938-155090379 processed_transcript
  ENST00000449545 TIAM2-011 154863011-154908866 processed_transcript
  ENST00000456877 TIAM2-003 155149109-155257200 protein_coding
  ENST00000460692 TIAM2-002 154833355-154908868 processed_transcript
  ENST00000461783 TIAM2-005 154832697-155257723 protein_coding
  ENST00000462408 TIAM2-018 155216966-155248002 protein_coding
  ENST00000528391 TIAM2-004 155149121-155257190 protein_coding
  ENST00000528535 TIAM2-006 155013922-155251985 protein_coding
  ENST00000529824 TIAM2-007 155129224-155257190 protein_coding
  ENST00000535064 TIAM2-013 154833345-154961479 processed_transcript
  ENST00000535231 TIAM2-015 155013764-155129384 protein_coding
  ENST00000535583 TIAM2-017 155121916-155129810 protein_coding
  ENST00000537845 TIAM2-022 155252919-155256686 retained_intron
  ENST00000538270 TIAM2-014 155013646-155129479 protein_coding
  ENST00000539296 TIAM2-020 155211226-155232903 processed_transcript
  ENST00000543712 TIAM2-019 155183315-155245636 nonsense_mediated_decay
  ENST00000545347 TIAM2-012 154995354-155129382 protein_coding
  ENST00000546145 TIAM2-021 155216966-155244830 retained_intron

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055J CIL_00055J_0001 CGP 6:154733325-155257723
CIL_00055I CIL_00055I_0001 CGP 6:154832697-155314493

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005057 IEA receptor signaling protein activity
GO:0005085 TAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0007165 IEA signal transduction
GO:0007264 TAS small GTPase mediated signal transduction
GO:0016020 IEA membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0042995 IEA cell projection
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040719 TIAM2 (1 of 2) T-cell lymphoma invasion and metastasis 2 protein_coding Danio_rerio
ENSDARG00000087780 tiam2a T-cell lymphoma invasion and metastasis 2a protein_coding Danio_rerio
ENSMUSG00000023800 Tiam2 T cell lymphoma invasion and metastasis 2 protein_coding Mus_musculus

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