C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein) alpha 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146535 GNA12 9606 - 7:2728112-2844324 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000275364 GNA12-001 2728112-2844324 protein_coding
  ENST00000407653 GNA12-005 2728566-2763140 protein_coding
  ENST00000407904 GNA12-002 2728561-2815259 protein_coding
  ENST00000447791 GNA12-006 2794967-2815258 protein_coding
  ENST00000471281 GNA12-007 2731023-2795145 processed_transcript
  ENST00000485329 GNA12-008 2731351-2760452 processed_transcript
  ENST00000491117 GNA12-004 2728561-2763209 processed_transcript
  ENST00000496740 GNA12-003 2729824-2763327 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000275364ENST00000407653ENST00000407904ENST00000491117
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000275364 8.691±0.00 11.007±0.00 6.567±5.73 5.772±5.22 5.952±4.24 2.555±0.00 4.832±0.00 1.610±1.10 3.337±2.29 1.498±0.00 6.607±3.86 15.548±9.38 8.985±1.32
ENST00000407653 N/A N/A N/A N/A N/A 0.430±0.00 N/A N/A N/A N/A 3.535±0.00 N/A N/A
ENST00000407904 N/A N/A 1.053±0.00 0.831±0.00 N/A N/A N/A 1.550±0.00 N/A 0.912±0.00 2.839±0.00 5.632±3.41 6.874±0.00
ENST00000491117 12.460±0.00 18.584±0.00 11.232±0.00 18.346±0.00 13.365±0.00 8.823±0.00 2.827±2.26 3.657±0.00 12.927±0.00 2.540±0.00 23.523±5.48 13.609±2.84 13.058±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RS CIL_0007RS_0001 VISTA 7:2311652-2915186
CIL_0002MB CIL_0002MB_0001 CGP 7:2679522-2844324
CIL_0002MC CIL_0002MC_0001 CGP 7:2728112-3043945

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0003924 IBA:IEA GTPase activity
GO:0004871 IBA:IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007266 IBA Rho protein signal transduction
GO:0007596 TAS blood coagulation
GO:0008360 IEA regulation of cell shape
GO:0010762 ISS regulation of fibroblast migration
GO:0019001 IEA guanyl nucleotide binding
GO:0030154 IEA cell differentiation
GO:0030168 TAS platelet activation
GO:0031526 IBA brush border membrane
GO:0031683 IBA:IEA G-protein beta/gamma-subunit complex binding
GO:0031752 IBA D5 dopamine receptor binding
GO:0032006 IMP regulation of TOR signaling
GO:0032434 IMP regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0042493 IEA response to drug
GO:0042733 IEA embryonic digit morphogenesis
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025826 gna12a guanine nucleotide binding protein (G protein) alpha 12a protein_coding Danio_rerio
ENSDARG00000037619 GNA12 (2 of 2) guanine nucleotide binding protein (G protein) alpha 12 protein_coding Danio_rerio
ENSMUSG00000000149 Gna12 guanine nucleotide binding protein, alpha 12 protein_coding Mus_musculus

Loading