C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: guanine nucleotide binding protein (G protein) alpha 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000275364 GNA12-001 ENSG00000146535 9606 - 7:2728112-2844324 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000275364
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000275364 8.691±0.00 11.007±0.00 6.567±5.73 5.772±5.22 5.952±4.24 2.555±0.00 4.832±0.00 1.610±1.10 3.337±2.29 1.498±0.00 6.607±3.86 15.548±9.38 8.985±1.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RS CIL_0007RS_0001 VISTA 7:2311652-2915186
CIL_0002MB CIL_0002MB_0001 CGP 7:2679522-2844324
CIL_0002MC CIL_0002MC_0001 CGP 7:2728112-3043945

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0003924 IBA:IEA GTPase activity
GO:0004871 IBA:IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007266 IBA Rho protein signal transduction
GO:0007596 TAS blood coagulation
GO:0008360 IEA regulation of cell shape
GO:0010762 ISS regulation of fibroblast migration
GO:0019001 IEA guanyl nucleotide binding
GO:0030154 IEA cell differentiation
GO:0030168 TAS platelet activation
GO:0031526 IBA brush border membrane
GO:0031683 IBA:IEA G-protein beta/gamma-subunit complex binding
GO:0031752 IBA D5 dopamine receptor binding
GO:0032006 IMP regulation of TOR signaling
GO:0032434 IMP regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0035556 IEA intracellular signal transduction
GO:0042493 IEA response to drug
GO:0042733 IEA embryonic digit morphogenesis
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000000153 Gna12-001 protein_coding Mus_musculus 0 1729
ENSMUST00000176035 Amz1-006 nonsense_mediated_decay Mus_musculus 0 501
ENSMUST00000106702 Gna13-002 protein_coding Mus_musculus 1e-37 163
ENSMUST00000020930 Gna13-001 protein_coding Mus_musculus 1e-37 163

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