C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EPH receptor A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000146904 EPHA1 9606 - 7:143390289-143408892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000275815 EPHA1-001 143391112-143408892 protein_coding
  ENST00000458129 EPHA1-008 143390289-143391391 processed_transcript
  ENST00000465208 EPHA1-006 143394210-143395601 retained_intron
  ENST00000479459 EPHA1-004 143397481-143398712 retained_intron
  ENST00000488068 EPHA1-002 143391411-143408805 retained_intron
  ENST00000494989 EPHA1-005 143394807-143396681 retained_intron
  ENST00000497891 EPHA1-003 143400826-143407650 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonKidneyLiverLungMuscleOvaryENST00000275815ENST00000488068ENST00000497891
Transcript ID Bladder Breast Colon Kidney Liver Lung Muscle Ovary
ENST00000275815 N/A 0.792±0.00 1.459±0.00 2.867±0.00 3.269±0.00 0.770±0.00 N/A 1.380±0.00
ENST00000488068 0.484±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000497891 N/A N/A N/A N/A N/A N/A 1.549±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074Q CIL_00074Q_0001 CGP 7:143353400-143391111
CIL_00074P CIL_00074P_0001 CGP 7:143381080-143408892

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001954 IDA positive regulation of cell-matrix adhesion
GO:0004672 IDA:IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005005 IDA transmembrane-ephrin receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007166 IDA cell surface receptor signaling pathway
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008284 IMP positive regulation of cell proliferation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0030335 IMP positive regulation of cell migration
GO:0030336 IDA negative regulation of cell migration
GO:0032314 IDA regulation of Rac GTPase activity
GO:0032862 IDA activation of Rho GTPase activity
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0045766 IMP positive regulation of angiogenesis
GO:0046777 IDA protein autophosphorylation
GO:0048013 IEA ephrin receptor signaling pathway
GO:0051496 ISS positive regulation of stress fiber assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000029859 Epha1 Eph receptor A1 protein_coding Mus_musculus

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