C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: O-linked N-acetylglucosamine (GlcNAc) transferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147162 OGT 9606 + X:71533083-71575897 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373701 OGT-002 71533123-71573816 protein_coding
  ENST00000373719 OGT-001 71533083-71575897 protein_coding
  ENST00000444774 OGT-011 71534301-71544624 protein_coding
  ENST00000455587 OGT-010 71537014-71555214 protein_coding
  ENST00000459760 OGT-008 71553621-71556778 processed_transcript
  ENST00000462638 OGT-006 71555813-71556968 retained_intron
  ENST00000466181 OGT-007 71556456-71557047 retained_intron
  ENST00000472270 OGT-009 71533128-71536657 retained_intron
  ENST00000474633 OGT-005 71564664-71567973 retained_intron
  ENST00000488174 OGT-003 71533104-71574655 retained_intron
  ENST00000498566 OGT-004 71533300-71546280 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373719ENST00000488174
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373719 1.942±0.00 N/A 2.063±0.00 8.082±5.91 7.122±4.80 7.055±4.53 5.773±1.27 4.081±1.72 5.143±3.86 7.277±3.61 5.489±0.48 10.875±0.52 1.956±0.44 2.616±1.14
ENST00000488174 1.247±0.00 3.284±0.00 1.629±0.00 3.587±2.81 11.021±0.00 13.161±0.00 2.038±0.68 3.662±0.00 5.148±0.00 15.637±0.00 2.091±1.03 6.229±2.43 1.114±0.59 3.061±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TR CIL_0000TR_0001 CGP X:71366239-71575897

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000123 IDA histone acetyltransferase complex
GO:0005515 IPI:IEA protein binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005815 IDA microtubule organizing center
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006110 IDA regulation of glycolytic process
GO:0006325 TAS chromatin organization
GO:0006493 IDA protein O-linked glycosylation
GO:0006915 IDA apoptotic process
GO:0007165 TAS signal transduction
GO:0007584 TAS response to nutrient
GO:0008047 IDA enzyme activator activity
GO:0008375 TAS acetylglucosaminyltransferase activity
GO:0016262 IDA protein N-acetylglucosaminyltransferase activity
GO:0030854 IMP positive regulation of granulocyte differentiation
GO:0031397 ISS negative regulation of protein ubiquitination
GO:0032868 IDA response to insulin
GO:0032922 ISS circadian regulation of gene expression
GO:0035020 IDA regulation of Rac protein signal transduction
GO:0042802 IEA identical protein binding
GO:0043085 IDA positive regulation of catalytic activity
GO:0043981 IDA histone H4-K5 acetylation
GO:0043982 IDA histone H4-K8 acetylation
GO:0043984 IDA histone H4-K16 acetylation
GO:0043995 IDA histone acetyltransferase activity (H4-K5 specific)
GO:0043996 IDA histone acetyltransferase activity (H4-K8 specific)
GO:0045862 IDA positive regulation of proteolysis
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046626 IDA regulation of insulin receptor signaling pathway
GO:0046972 IDA histone acetyltransferase activity (H4-K16 specific)
GO:0048015 IDA phosphatidylinositol-mediated signaling
GO:0051571 IDA positive regulation of histone H3-K4 methylation
GO:0061087 IMP positive regulation of histone H3-K27 methylation
GO:0070688 IDA MLL5-L complex
GO:0071300 IMP cellular response to retinoic acid
GO:0080182 IMP histone H3-K4 trimethylation
GO:0090526 ISS regulation of gluconeogenesis involved in cellular glucose homeostasis
GO:0097363 ISS protein O-GlcNAc transferase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057702 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 protein_coding Danio_rerio
ENSDARG00000095552 ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 protein_coding Danio_rerio
ENSMUSG00000034160 Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) protein_coding Mus_musculus

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