C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034160 Ogt 10090 + X:101640060-101684351 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044475 Ogt-001 101640064-101684351 protein_coding
  ENSMUST00000119299 Ogt-002 101640060-101682940 protein_coding
  ENSMUST00000147635 Ogt-007 101655345-101683158 processed_transcript
  ENSMUST00000150161 Ogt-004 101640108-101654586 retained_intron
  ENSMUST00000153979 Ogt-006 101640094-101654318 processed_transcript
  ENSMUST00000155713 Ogt-003 101640062-101652877 retained_intron
  ENSMUST00000155792 Ogt-005 101640140-101652894 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044475ENSMUST00000119299ENSMUST00000147635
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044475 17.993±4.23 14.847±4.19 65.867±15.52 88.756±22.20 22.433±11.06 7.252±2.61 12.839±1.32 12.010±3.44 17.564±13.48 19.089±0.95 14.520±6.30 24.435±6.93 23.578±6.79 3.579±1.09
ENSMUST00000119299 15.704±1.39 N/A N/A N/A 23.691±10.93 10.708±3.43 N/A N/A N/A N/A N/A 24.808±8.25 7.441±0.00 2.132±0.69
ENSMUST00000147635 N/A 12.932±2.48 N/A 12.675±0.00 13.733±1.91 8.091±1.82 4.731±0.00 N/A 2.919±0.00 12.010±0.00 N/A 19.327±2.17 7.024±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TR CIL_0000TR_0002 CGP X:101532734-101684351

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000123 ISS histone acetyltransferase complex
GO:0003824 ISS catalytic activity
GO:0005515 IPI protein binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005622 TAS intracellular
GO:0005634 ISS nucleus
GO:0005737 TAS cytoplasm
GO:0005815 IEA microtubule organizing center
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0006110 ISS regulation of glycolytic process
GO:0006493 ISS protein O-linked glycosylation
GO:0006915 ISS apoptotic process
GO:0008047 IEA enzyme activator activity
GO:0008080 TAS N-acetyltransferase activity
GO:0016262 ISS protein N-acetylglucosaminyltransferase activity
GO:0030854 IEA positive regulation of granulocyte differentiation
GO:0031397 IDA negative regulation of protein ubiquitination
GO:0032868 IEA response to insulin
GO:0032922 IMP circadian regulation of gene expression
GO:0035020 IEA regulation of Rac protein signal transduction
GO:0043085 IEA positive regulation of catalytic activity
GO:0043981 ISS histone H4-K5 acetylation
GO:0043982 ISS histone H4-K8 acetylation
GO:0043984 ISS histone H4-K16 acetylation
GO:0043995 ISS histone acetyltransferase activity (H4-K5 specific)
GO:0043996 ISS histone acetyltransferase activity (H4-K8 specific)
GO:0045862 ISS positive regulation of proteolysis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046626 IEA regulation of insulin receptor signaling pathway
GO:0046972 ISS histone acetyltransferase activity (H4-K16 specific)
GO:0048015 ISS phosphatidylinositol-mediated signaling
GO:0051571 IEA positive regulation of histone H3-K4 methylation
GO:0061087 ISS positive regulation of histone H3-K27 methylation
GO:0070688 IEA MLL5-L complex
GO:0071300 IEA cellular response to retinoic acid
GO:0080182 IEA histone H3-K4 trimethylation
GO:0090526 IMP regulation of gluconeogenesis involved in cellular glucose homeostasis
GO:0097363 IMP protein O-GlcNAc transferase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057702 ogt.1 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1 protein_coding Danio_rerio
ENSDARG00000095552 ogt.2 O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 2 protein_coding Danio_rerio
ENSG00000147162 OGT O-linked N-acetylglucosamine (GlcNAc) transferase protein_coding Homo_sapiens

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