C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, nicotinic, beta 3 (neuronal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000147432 CHRNB3 9606 + 8:42697376-42737407 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289957 CHRNB3-001 42697419-42737407 protein_coding
  ENST00000531610 CHRNB3-003 42697376-42708758 processed_transcript
  ENST00000534391 CHRNB3-002 42697376-42710435 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalKidneyLungOvaryENST00000289957ENST00000531610
Transcript ID Adipose Adrenal Kidney Lung Ovary
ENST00000289957 N/A N/A 0.491±0.00 0.029±0.00 0.011±0.00
ENST00000531610 0.087±0.00 0.119±0.00 0.117±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002IT CIL_0002IT_0001 CGP 8:42697376-42796392

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005886 TAS plasma membrane
GO:0005892 IEA acetylcholine-gated channel complex
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0006812 TAS cation transport
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007271 TAS synaptic transmission, cholinergic
GO:0008144 IEA drug binding
GO:0015267 TAS channel activity
GO:0016020 IEA membrane
GO:0016021 NAS:IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0042166 IEA acetylcholine binding
GO:0043005 IEA neuron projection
GO:0045211 IEA postsynaptic membrane
GO:0051291 IEA protein heterooligomerization
GO:0055085 TAS transmembrane transport
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038508 chrnb3b cholinergic receptor, nicotinic, beta polypeptide 3b protein_coding Danio_rerio
ENSDARG00000052764 chrnb3a cholinergic receptor, nicotinic, beta polypeptide 3a protein_coding Danio_rerio
ENSMUSG00000031492 Chrnb3 cholinergic receptor, nicotinic, beta polypeptide 3 protein_coding Mus_musculus

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