C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin E synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148344 PTGES 9606 - 9:129738331-129753047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340607 PTGES-001 129738331-129753047 protein_coding
  ENST00000481476 PTGES-002 129738331-129753019 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340607ENST00000481476
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340607 31.107±0.00 15.842±0.00 1.392±0.00 0.617±0.06 6.466±4.66 5.580±4.68 0.403±0.38 1.124±1.05 1.203±1.04 3.517±3.18 0.678±0.00 5.191±3.34 101.080±29.88 11.404±4.88
ENST00000481476 N/A 2.361±0.00 N/A 0.435±0.00 N/A N/A N/A 0.935±0.00 N/A 0.902±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005UC CIL_0005UC_0001 CGP 9:129665641-129753047
CIL_0005UB CIL_0005UB_0001 CGP 9:129738331-129811281

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IDA prostaglandin biosynthetic process
GO:0002526 IEA acute inflammatory response
GO:0002544 IEA chronic inflammatory response
GO:0005641 IEA nuclear envelope lumen
GO:0005737 IEA cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006693 TAS prostaglandin metabolic process
GO:0007165 NAS signal transduction
GO:0008285 IEA negative regulation of cell proliferation
GO:0014070 IEA response to organic cyclic compound
GO:0016020 TAS membrane
GO:0016021 IDA integral component of membrane
GO:0019369 TAS arachidonic acid metabolic process
GO:0019371 TAS cyclooxygenase pathway
GO:0032496 IEA response to lipopolysaccharide
GO:0032526 IEA response to retinoic acid
GO:0034097 IEA response to cytokine
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043295 IDA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050220 IDA prostaglandin-E synthase activity
GO:0051592 IEA response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020136 ptges prostaglandin E synthase protein_coding Danio_rerio
ENSMUSG00000050737 Ptges prostaglandin E synthase protein_coding Mus_musculus

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