C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin E synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050737 Ptges 10090 - 2:30889471-30929863 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056046 Ptges-002 30892282-30901788 protein_coding
  ENSMUST00000102852 Ptges-001 30889471-30903297 protein_coding
  ENSMUST00000126588 Ptges-003 30892488-30897469 processed_transcript
  ENSMUST00000132244 Ptges-004 30892296-30929863 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056046ENSMUST00000102852ENSMUST00000126588ENSMUST00000132244
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056046 44.091±14.65 18.650±6.14 N/A 0.572±0.09 34.924±2.12 5.239±1.39 0.986±0.36 7.637±1.45 0.321±0.33 11.439±1.55 N/A 29.305±4.36 11.952±12.20 4.696±0.04
ENSMUST00000102852 26.181±7.95 5.305±0.49 20.082±1.05 0.801±0.13 15.928±3.87 3.542±0.96 0.489±0.18 9.072±0.85 0.175±0.26 8.007±0.61 0.502±0.21 26.871±9.59 5.205±3.40 1.001±0.95
ENSMUST00000126588 N/A N/A N/A N/A N/A 6.547±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000132244 N/A N/A N/A N/A N/A N/A N/A N/A 0.114±0.03 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005UC CIL_0005UC_0002 CGP 2:30834972-30929863
CIL_0005UB CIL_0005UB_0002 CGP 2:30889471-30959015

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 ISS prostaglandin biosynthetic process
GO:0002526 IEA acute inflammatory response
GO:0002544 IEA chronic inflammatory response
GO:0004667 TAS prostaglandin-D synthase activity
GO:0005641 IDA nuclear envelope lumen
GO:0005737 IDA cytoplasm
GO:0006693 IDA prostaglandin metabolic process
GO:0008285 IGI negative regulation of cell proliferation
GO:0014070 IEA response to organic cyclic compound
GO:0016021 ISS integral component of membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0032526 IEA response to retinoic acid
GO:0034097 IEA response to cytokine
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043295 ISS glutathione binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050220 ISS prostaglandin-E synthase activity
GO:0051592 IEA response to calcium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020136 ptges prostaglandin E synthase protein_coding Danio_rerio
ENSG00000148344 PTGES prostaglandin E synthase protein_coding Homo_sapiens

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