C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NACC family member 2, BEN and BTB (POZ) domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000148411 NACC2 9606 - 9:136006537-136095285 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000277554 NACC2-201 136006537-136095285 protein_coding
  ENST00000371753 NACC2-001 136006537-136050580 protein_coding
  ENST00000467669 NACC2-002 136016291-136019480 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000277554ENST00000371753
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000277554 6.221±0.00 2.850±0.00 N/A 2.944±2.13 5.599±3.24 3.347±1.26 6.629±5.20 3.545±1.63 7.106±0.63 7.663±0.00 5.798±3.85 2.309±1.17 N/A N/A
ENST00000371753 N/A 5.413±0.00 0.413±0.00 11.390±6.68 N/A 4.543±0.00 N/A 0.905±0.00 N/A 1.338±0.00 N/A 6.954±7.05 1.295±0.25 4.104±1.42

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001F0 CIL_0001F0_0001 CGP 9:135932969-136095285

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001076 IDA RNA polymerase II transcription factor binding transcription factor activity
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0004407 IDA histone deacetylase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008284 ISS positive regulation of cell proliferation
GO:0008285 IDA negative regulation of cell proliferation
GO:0010608 IMP posttranscriptional regulation of gene expression
GO:0016575 IDA histone deacetylation
GO:0016581 IDA NuRD complex
GO:0016604 ISS nuclear body
GO:0034629 IDA cellular protein complex localization
GO:0042803 IDA protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0051260 ISS protein homooligomerization
GO:1900477 IDA negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter
GO:1902231 IDA positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077425 NACC2 NACC family member 2, BEN and BTB (POZ) domain containing protein_coding Danio_rerio
ENSMUSG00000026932 Nacc2 nucleus accumbens associated 2, BEN and BTB (POZ) domain containing protein_coding Mus_musculus

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